230 Objectives: To evaluate the myocardial sympathetic denervation by using L-3, 4-
dihydroxy-6-F-18fluorodihydroxyphenylalanine (18F-FDOPA) PET-CT in patients with early …

The uptake of 6-18F-fluorodopamine by cardiac noradrenergic nerves enables visualization
of the sympathetic innervation of the left ventricular myocardium by PET. Patients with …

Purpose To determine whether cardiac sympathetic denervation in idiopathic Parkinson
disease (IPD) affects the left ventricle in a distinct regional pattern versus a more global …

The objective of this study was to detect regional patterns of cardiac sympathetic
denervation in idiopathic Parkinson disease (IPD) using 11C-hydroxyephedrine (11C-HED) …

Scintigraphic imaging with 123I-metaiodobenzylguanidine (123I-MIBG) has demonstrated
extensive losses of cardiac sympathetic neurons in idiopathic Parkinson's disease (IPD). In …

551 Objectives Extensive cardiac sympathetic neuronal loss occurs in IPD. PET imaging
with 11 C-meta-hydroxyephedrine (11 C-HED) allows quantitative analysis of sympathetic …

Autonomic involvement, including cardiac denervation, may precede the motor symptoms of
Parkinson's disease by several years. L-3, 4-dihydroxy-6-[18F] fluoro-phenylalanine is a …

Aim The aim of our study was to investigate the relationship between myocardial
sympathetic degeneration and nigrostriatal impairment in patients affected by Parkinson's …

1585 Objectives To detect regional patterns of cardiac sympathetic denervation in IPD using
11 C-HED PET and to determine the rate of decline on serial studies. Methods 62 cardiac 11 …

Background Dysfunction and denervation of myocardial nor-adrenergic sympathetic
neurons has been documented in IPD patients with dysautonomia. The aim of this study was …