Radionuclide imaging monitoring hypoxia tumor microenvironment improved homologous targeting probe for enhancing photodynamic therapy
H Fang, Y Gai, S Wang, Y Zhang, X Lan - 2020 - Soc Nuclear Med
1058 Objectives: Photodynamic therapy (PDT) efficacy is often limited by the hypoxia of
tumor microenvironment, while perfluorocarbon (PFTBA) has extremely high oxygen …
tumor microenvironment, while perfluorocarbon (PFTBA) has extremely high oxygen …
Glutathione depletion and dual-model oxygen balance disruption for photodynamic therapy enhancement
W Li, J Yong, Y Xu, Y Wang, Y Zhang, H Ren… - Colloids and Surfaces B …, 2019 - Elsevier
Photodynamic therapy (PDT) is a prospective approach to cure tumor diseases. However,
tumor micro-environment is notably characterized with severe hypoxia and high expression …
tumor micro-environment is notably characterized with severe hypoxia and high expression …
Oxygen self-sufficient fluorinated polypeptide nanoparticles for NIR imaging-guided enhanced photodynamic therapy
A major hindrance for photodynamic therapy (PDT) to achieve higher efficiency is the
hypoxia environment in the tumor area and the PDT-induced continuous consumption of …
hypoxia environment in the tumor area and the PDT-induced continuous consumption of …
Mitochondria-targeting oxygen-sufficient perfluorocarbon nanoparticles for imaging-guided tumor phototherapy
S Chen, B Huang, W Pei, L Wang, Y Xu… - International journal of …, 2020 - Taylor & Francis
Background Although photothermal therapy (PTT) and photodynamics therapy (PDT) have
both made excellent progress in tumor therapy, the effectiveness of using PTT or PDT alone …
both made excellent progress in tumor therapy, the effectiveness of using PTT or PDT alone …
IR780 Conjugated TSPO-binding Ligand Loaded pH-sensitive Nanoplatform for Effective TSPO Targeted Photodynamic Therapy
M Jeon, SH Lee, W Lee, BC Lee, SE Kim, HJ Im - 2021 - Soc Nuclear Med
1272 Purpose: Translocator protein (TSPO) is one of the emerging cancer biomarkers and
has been shown to be associated with poor prognosis in a variety of malignancies …
has been shown to be associated with poor prognosis in a variety of malignancies …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Perfluorocarbon-based O 2 nanocarrier for efficient photodynamic therapy
Tumor hypoxia is considered as one of the major factors that limit the efficiency of
photodynamic therapy (PDT), in which oxygen (O2) is needed to generate singlet oxygen …
photodynamic therapy (PDT), in which oxygen (O2) is needed to generate singlet oxygen …
[HTML][HTML] Strategies to improve photodynamic therapy efficacy by relieving the tumor hypoxia environment
Z Shen, Q Ma, X Zhou, G Zhang, G Hao, Y Sun… - NPG Asia …, 2021 - nature.com
Photodynamic therapy (PDT) is an emerging technology for tumor treatment in which
photosensitizer (PS)-mediated light irradiation reduces oxygen, producing high levels of …
photosensitizer (PS)-mediated light irradiation reduces oxygen, producing high levels of …
Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia
Hypoxia exists in most malignant tumors and often contributes to therapy resistance,
especially for aerobic treatments such as photodynamic therapy (PDT) and radiotherapy …
especially for aerobic treatments such as photodynamic therapy (PDT) and radiotherapy …
Perfluorocarbon‐loaded and redox‐activatable photosensitizing agent with oxygen supply for enhancement of fluorescence/photoacoustic imaging guided tumor …
DR Hu, L Zhong, MY Wang, HH Li, Y Qu… - Advanced Functional …, 2019 - Wiley Online Library
The wide clinical application of photodynamic therapy (PDT) is hampered by poor water
solubility, low tumor selectivity, and nonspecific activation of photosensitizers, as well as …
solubility, low tumor selectivity, and nonspecific activation of photosensitizers, as well as …