[PDF][PDF] Hepatic extraction efficiency and excretion rate of technetium-99m-mebrofenin in dogs

GB Daniel, A Bahr, JA Dykes, R DeNovo… - Journal of Nuclear …, 1996 - Soc Nuclear Med
Quantitative hepatobiliary scintigraphy aids in the diagnosis of hepatic disease. Two
scintigraphic parameters that have great value in discriminating between hepatocellular and …

[PDF][PDF] Hepatic extraction efficiency of technetium-99m-mebrofenin in the dog with toxic-induced acute liver disease

GB Daniel, RC DeNovo, AE Schultze… - Journal of Nuclear …, 1998 - Soc Nuclear Med
MATERIALS AND METhODS Ten conditioned, adult mongrel dogs (6 female, 4 male; body
weight range 14.5 — 29.1 kg; mean 21.39 kg) were obtained from the laboratory animal …

[PDF][PDF] Quantification of hepatobiliary function as an integral part of imaging with technetium-99m-mebrofenin in health and disease

E Doo, GT Krishnamurthy, MJ Eklem… - Journal of Nuclear …, 1991 - Soc Nuclear Med
MATERIALS AND METhODS Eighteen adult healthy volunteers (controls) and 24 patients
were studied. The control subjects (12 males and 6 females) ranged in age from 23 to 71 yr …

EVALUATION OF HEART TIME‐ACTIVITY CURVES AS A PREDICTOR OF HEPATIC EXTRACTION OF 99mTc‐MEBROFENIN IN DOGS

GB Daniel, R DeNovo, A Bahr… - Veterinary Radiology & …, 2001 - Wiley Online Library
In this study, heart time‐activity curve, created following intravenous injection of 99mTc‐
mebrofenin were used to quantify hepatic function in normal dogs and dogs with induced …

Validation of deconvolutional analysis for the measurement of hepatic function in dogs with toxic‐induced liver disease

GB Daniel, R Denovo, AE Schultze… - Veterinary Radiology …, 1998 - Wiley Online Library
The extraction of the hepatobiliary radiopharmaceutical 99mTc‐mebrofenin (Choletec) by
the liver can be used to evaluate the severity of hepatocellular disease. The hepatic …

A new method for quantification of hepatobiliary scintigraphy using 99mTc—mebrofenin. A comparative study

JMP Lima, JJP Lima, J Isidoro, P Lapa - Revista Española de Medicina …, 2003 - Elsevier
A method based upon the application of mathematical techniques of deconvolution on the
classical compartmental model for the quantitative study of liver function from hepatobiliary …

QUANTITATIVE HEPATOBILIARY SCINTIGRAPHY WITH DECONVOLUTIONAL ANALYSIS FOR THE MEASUREMETN OF HEPATIC FUNCTION IN DOGS

A Bahr, GB Daniel, R DeNovo, K Young… - Veterinary Radiology …, 1996 - Wiley Online Library
A nuclear medicine procedure that has been used for quantification of hepatocyte function in
man is applied and validated in the dog. This procedure employs deconvolutional analysis …

Preoperative assessment of liver function: a comparison of 99mTc‐Mebrofenin scintigraphy with indocyanine green clearance test

D Erdogan, BHM Heijnen, RJ Bennink, M Kok… - Liver …, 2004 - Wiley Online Library
Background/aims: The indocyanine green (ICG) clearance test is the most frequently used
test for preoperative assessment of liver parenchymal function but has its limitations. The …

[PDF][PDF] Hepatic clearance mechanism of Tc-99m-HIDA and its effect on quantitation of hepatobiliary function: concise communication

E Harvey, M Loberg, J Ryan, S Sikorski… - Journal of Nuclear …, 1979 - Soc Nuclear Med
METHODS Anionic clearance mechanism. In three female dogs the distribution and
elimination kinetics of I-131RB and Tc-HIDA were simultaneously evaluated be fore and …

Uptake of technetium 99m hepatobiliary imaging agents by cultured rat hepatocytes

JA Lan, LR Chervu, KL Johansen, AW Wolkoff - Gastroenterology, 1988 - Elsevier
Quantitation of initial uptake of the cholescintigraphy agents, 99m Tc-Lidofenin, 99m Tc-
Disofenin, 99m Tc-Mebrofenin, and 99m Tc-Arclofenin, in short-term cultured rat hepatocytes …