[PDF][PDF] RadioimmunoPET: detection of colorectal carcinoma with positron-emitting copper-64-labeled monoclonal antibody

GW Philpott, SW Schwarz, CJ Anderson… - Journal of Nuclear …, 1995 - Soc Nuclear Med
Detection of tumor foci may be improved by combining the selective tumor-targeting
properties of a monoclonal antibody with the supetior sensitivity and contrast resolutiOnof …

Radioimmuno positron emission tomography with monoclonal antibodies: A new approach to quantifying: in vivo: tumour concentration and biodistribution for …

G Westera, HW Reist, F Buchegger… - Nuclear medicine …, 1991 - journals.lww.com
Radioimmunodetection of tumours with monoclonal antibodies is becoming an established
procedure. Positron emission tomography (PET) shows better resolution than normal …

FDG PET and immunoscintigraphy with 99mTc-labeled antibody fragments for detection of the recurrence of colorectal carcinoma

P Willkomm, H Bender, M Bangard… - Journal of Nuclear …, 2000 - Soc Nuclear Med
The aim of this study was to compare FDG PET with a new monoclonal antibody–based
imaging agent that comprises an anti–carcinoembryonic antigen (CEA) monoclonal …

[PDF][PDF] The applications of PET in clinical oncology

LG Strauss, PS Conti - Journal of nuclear medicine, 1991 - Soc Nuclear Med
The colorectaltumor is one ofthe most common tumors in oncology. Abdominoperineal
resection of colorectal carcinoma is followed by local recurrence in 25%-30% of all …

Promising clinical performance of pretargeted immuno-PET with anti-CEA bispecific antibody and gallium-68-labelled IMP-288 peptide for imaging colorectal cancer …

Y Touchefeu, C Bailly, E Frampas, T Eugène… - European Journal of …, 2021 - Springer
Introduction This pilot study evaluated the imaging performance of pretargeted
immunological positron emission tomography (immuno-PET) using an anti …

124I-huA33 antibody PET of colorectal cancer

JA Carrasquillo, N Pandit-Taskar… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Humanized A33 (huA33) is a promising monoclonal antibody that recognizes A33 antigen,
which is present in more than 95% of colorectal cancers and in normal bowel. In this study …

Positron emission tomography and colorectal cancer

THA Arulampalam, DC Costa, M Loizidou… - British journal of …, 2001 - Wiley Online Library
Background: The oncological applications of positron emission tomography (PET) have
gained widespread acceptance. This rapidly evolving technology has been applied …

Imaging cancer using PET—the effect of the bifunctional chelator on the biodistribution of a 64Cu-labeled antibody

JLJ Dearling, SD Voss, P Dunning, E Snay… - Nuclear medicine and …, 2011 - Elsevier
INTRODUCTION: Use of copper radioisotopes in antibody radiolabeling is challenged by
reported loss of the radionuclide from the bifunctional chelator used to label the protein. The …

[PDF][PDF] Comparison of complete versus fragmented technetium-99m-labeled anti-CEA monoclonal antibodies for immunoscintigraphy in colorectal cancer

TM Behr, WS Becker, HJ Bair, MW Klein… - Journal of Nuclear …, 1995 - Soc Nuclear Med
Thegoalof thisstudywasto intraindMduallycomparecomplete
versusfragmenteddirectlylabeled@ Tcmonoclonalanti-CEA antibodyw@ irespectto …

124I-huA33 antibody uptake is driven by A33 antigen concentration in tissues from colorectal cancer patients imaged by immuno-PET

JA O'Donoghue, PM Smith-Jones… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The primary aim of this analysis was to examine the quantitative features of antibody–
antigen interactions in tumors and normal tissue after parenteral administration of antitumor …