Quantitative radionuclide studies of bone

GM Blake, ML Frost, I Fogelman - Journal of Nuclear Medicine, 2009 - Soc Nuclear Med
Nuclear Medicine, Uchida et al. present results from a prospective study using 18F-fluoride
PET to assess the effects of bisphosphonate treatment on bone metabolism in patients with …

Effects of alendronate on bone metabolism in glucocorticoid-induced osteoporosis measured by 18F-fluoride PET: a prospective study

K Uchida, H Nakajima, T Miyazaki… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Osteoporosis represents a significant side effect of glucocorticoid therapy, and alendronate
has been reported to prevent this glucocorticoid-induced osteoporosis. Functional imaging …

Radionuclide studies of bone metabolism: do bone uptake and bone plasma clearance provide equivalent measurements of bone turnover?

GM Blake, M Siddique, ML Frost, AEB Moore… - Bone, 2011 - Elsevier
Quantitative radionuclide imaging using 18F-fluoride positron emission tomography (18F-
PET) or 99mTc-methylene diphosphonate (99mTc-MDP) bone scans provides a novel tool …

The precision and sensitivity of 18F-fluoride PET for measuring regional bone metabolism: a comparison of quantification methods

M Siddique, ML Frost, GM Blake… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The planning of research studies requires an understanding of the minimum number of
subjects required. The aim of this study was to evaluate different methods of analyzing 18F …

[CITATION][C] Quantification of skeletal Tc-99m labeled phosphates to detect metabolic bone disease

RA Holmes - Journal of Nuclear Medicine, 1978 - Soc Nuclear Med
As a highly sensitive indicator of disturbed bone metabolism, the Tc-99m-labeled
phosphates have dramatically established their role in the clinical assessment of bone …

Quantitative PET imaging using 18F sodium fluoride in the assessment of metabolic bone diseases and the monitoring of their response to therapy

GM Blake, M Siddique, ML Frost, AEB Moore… - PET clinics, 2012 - pet.theclinics.com
Over the past 20 years, a series of increasingly potent new treatments have been licensed
for the prevention of osteoporotic fractures (Table 1). 1–8 The most commonly used class of …

[PDF][PDF] Effects of radiation therapy on bone lesions as measured by 99mTc-diphosphonate

FP Castronovo, MS Potsaid… - Journal of Nuclear …, 1973 - Soc Nuclear Med
MATERIALS AND METHODS Our initial study was carried out in an adult white man (MGH#
1670755) who had a bony metastases from an adenocarcinoma of the lung to the spine and …

Long-term precision of 18F-fluoride PET skeletal kinetic studies in the assessment of bone metabolism

ML Frost, GM Blake, SJ Park-Holohan… - Journal of Nuclear …, 2008 - Soc Nuclear Med
18F-Fluoride PET allows noninvasive evaluation of regional bone metabolism and has the
potential to become a useful tool for assessing patients with metabolic bone disease and …

[PDF][PDF] Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET

RA Hawkins, Y Choi, SC Huang, CK Hoh… - Journal of Nuclear …, 1992 - Soc Nuclear Med
Investigators have previously studied the kinetics of ['8F] fluoride ion in bone with plasma
clearance and tissue sampling techniques in animals (14, 15) and plasma clear ance …

[PDF][PDF] Estimating the risk of osteoporosis

HW Wahner - Journal of Nuclear Medicine, 1994 - Soc Nuclear Med
BiochemicalMarkers of Bone Turnover time of menopause lose bone at an
acceleratedrateover 12yr (18), which suggests that the accelerated loss is not just an …