Optimal quality 131I-monoclonal antibodies on high-dose labeling in a large reaction volume and temporarily coating the antibody with IODO-GEN
GW Visser, RP Klok, JWK Gebbinck… - Journal of Nuclear …, 2001 - Soc Nuclear Med
A novel, facile procedure for efficient coupling of high doses of 131I to monoclonal
antibodies (MAbs) was developed with minimal chemical and radiation damage. Methods …
antibodies (MAbs) was developed with minimal chemical and radiation damage. Methods …
131I-rituximab: relationship between immunoreactivity and specific activity
AO Schaffland, F Buchegger, M Kosinski… - Journal of Nuclear …, 2004 - Soc Nuclear Med
As part of a search for optimal conditions for radioimmunotherapy of lymphoma, rituximab
was labeled with 2 different specific activities of 131I and immunoreactivity was …
was labeled with 2 different specific activities of 131I and immunoreactivity was …
Improved iodine radiolabels for monoclonal antibody therapy
R Stein, SV Govindan, MJ Mattes, S Chen, L Reed… - Cancer Research, 2003 - AACR
A major disadvantage of 131iodine (I)-labeled monoclonal antibodies (MAbs) for
radioimmunotherapyhas been the rapid diffusion of iodotyrosine from target cells …
radioimmunotherapyhas been the rapid diffusion of iodotyrosine from target cells …
High-quality 124I-labelled monoclonal antibodies for use as PET scouting agents prior to 131I-radioimmunotherapy
I Verel, GWM Visser, MJWD Vosjan, R Finn… - European journal of …, 2004 - Springer
Abstract Purpose Monoclonal antibodies (MAbs) labelled with 124 I are an attractive option
for quantitative imaging with positron emission tomography (PET) in a scouting procedure …
for quantitative imaging with positron emission tomography (PET) in a scouting procedure …
[PDF][PDF] Improved clearance of radiolabeled biotinylated monoclonal antibody following the infusion of avidin as a “chase” without decreased accumulation in the target …
H Kobayashi, H Sakahara, M Hosono… - Journal of Nuclear …, 1994 - Soc Nuclear Med
The techniques of rad@ mmuncimaglng and radioimmuno therapysufferfromprolongedhighbackgroun…
cause intravenouslyinjectedanthOdieSremaininthe circulation and inthe organs far …
cause intravenouslyinjectedanthOdieSremaininthe circulation and inthe organs far …
Comparison of the distribution and binding of monoclonal antibodies labeled with 131-iodine or 111-indium
D Buchsbaum, B Randall, D Hanna, R Chandler… - European journal of …, 1985 - Springer
The distribution of two monoclonal antibodies with reactivity against human
leukemia/lymphoma associated antigens (BA-1 antibody) and carcinoembryonic antigen …
leukemia/lymphoma associated antigens (BA-1 antibody) and carcinoembryonic antigen …
Fully automated 89Zr labeling and purification of antibodies
AJ Poot, KWA Adamzek, AD Windhorst… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Dozens of monoclonal antibodies (mAbs) have been approved for clinical use, and
hundreds more are under development. To support these developments and facilitate a …
hundreds more are under development. To support these developments and facilitate a …
188Re-direct labeling of monoclonal antibodies for radioimmunotherapy of solid tumors: biodistribution, normal organ dosimetry, and toxicology
N Iznaga-Escobar - Nuclear medicine and biology, 1998 - Elsevier
The increased interest in the availability of radionuclides for therapy has resulted from the
recent success and potential importance of radiolabeled antibodies for both diagnosis and …
recent success and potential importance of radiolabeled antibodies for both diagnosis and …
[PDF][PDF] Radioimmunotherapy with intravenously administered 131I-labeled chimeric monoclonal antibody MOv18 in patients with ovarian cancer
I van Zanten-Przybysz, CF Molthoff… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Radioimmunotherapy with Intravenously Administered 131I-LabeledChimeric Monoclonal
Antibody MOvlS in Patients with Ovarian Cance Page 1 Radioimmunotherapy with Intravenously …
Antibody MOvlS in Patients with Ovarian Cance Page 1 Radioimmunotherapy with Intravenously …
Influence of dose and schedule on the therapeutic efficacy of 131I‐labelled monoclonal antibody 139H2 in a human ovarian cancer xenograft model
CPM Molthoff, HM Pinedo… - … journal of cancer, 1992 - Wiley Online Library
The therapeutic efficacy of various doses and schedules of 131I‐labelled anti‐episialin
monoclonal antibody (MAb) 139H2 was assessed in the NIH: OVCAR‐3 human ovarian …
monoclonal antibody (MAb) 139H2 was assessed in the NIH: OVCAR‐3 human ovarian …
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