Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease

G El Fakhri, MF Kijewski, MS Albert… - Journal of Nuclear …, 2004 - Soc Nuclear Med
We investigated the impact of the quantitation and reconstruction protocol on clinical tasks.
The performance of standard clinical reconstruction procedures in discrimination tasks …

[PDF][PDF] The discriminant value of semiquantitative SPECT data in mild Alzheimer's disease

D O'Mahony, J Coffey, J Murphy, N O'Hare… - Journal of Nuclear …, 1994 - Soc Nuclear Med
The Discriminant Value of Semiquantitative SPECT Data in Mild Alzheimer's Disease Page 1
The Discriminant Value of Semiquantitative SPECT Data in Mild Alzheimer's Disease Denis …

Direct comparison of spatially normalized PET and SPECT scans in Alzheimer's disease

K Herholz, H Schopphoff, M Schmidt… - Journal of Nuclear …, 2002 - Soc Nuclear Med
Hexamethylpropyleneamine oxime (HMPAO) SPECT and 18F-FDG PET depict similar
aspects of perfusion and metabolic abnormalities in Alzheimer's disease (AD), but the …

Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer's disease: a clinical evaluation of linearization correction

T Mitsumoto, N Ohya, A Ichimiya, Y Sakaguchi… - Annals of nuclear …, 2009 - Springer
Objective This study examined the influence of linearization correction (LC) on brain
perfusion single-photon emission computed tomography (SPECT) for the diagnosis of …

[PDF][PDF] Quantitative brain SPECT in Alzheimer's disease and normal aging

KA Johnson, MF Kijewski, JA Becker… - Journal of Nuclear …, 1993 - Soc Nuclear Med
Disease and Normal Aging Page 1 To improvethe diagnosticutilityof brainsingle-photonemission
computed tomography (SPECT) inAlzheimer's disease (AD), we have developed and evaluated …

Effects of partial volume correction on discrimination between very early Alzheimer's dementia and controls using brain perfusion SPECT

H Kanetaka, H Matsuda, T Asada, T Ohnishi… - European journal of …, 2004 - Springer
We assessed the accuracy of brain perfusion single-photon emission computed tomography
(SPECT) in discriminating between patients with probable Alzheimer's disease (AD) at the …

Preclinical prediction of Alzheimer's disease using SPECT

KA Johnson, K Jones, BL Holman, JA Becker… - Neurology, 1998 - AAN Enterprises
Background Regional cerebral perfusion measured by single photon emission computed
tomography (SPECT) was examined as a preclinical predictor of the development of …

MRI-guided SPECT perfusion measures and volumetric MRI in prodromal Alzheimer disease

G El Fakhri, MF Kijewski, KA Johnson… - Archives of …, 2003 - jamanetwork.com
Objective To identify group differences in the prodromal phase of Alzheimer disease (AD)
using quantitative single-photon emission computed tomography (SPECT) perfusion and …

The need of appropriate brain SPECT templates for SPM comparisons

S Morbelli, G Rodriguez, A Mignone… - … Quarterly Journal of …, 2008 - search.proquest.com
Statistical parametric mapping (SPM) is used worldwide to compare brain perfusion single
photon emission computed tomography (SPECT) data. The default template within the SPM …

Statistical parametric mapping of 99mTc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake

D Soonawala, T Amin, KP Ebmeier, JD Steele… - Neuroimage, 2002 - Elsevier
Background: For a quantitative comparison of images obtained during 99mTc-
hexamethylpropylene amine oxime (HMPAO) single-photon emission computed …