Radiolabeled humanized anti-CD3 monoclonal antibody visilizumab for imaging human T-lymphocytes

G Malviya, C D'Alessandria, E Bonanno… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Visilizumab is an IgG2 humanized monoclonal antibody (mAb) characterized by non-FcγR
binding and specific to the CD3 antigen, expressed on more than 95% of circulating resting …

Comparison of immunoscintigraphy, efficacy, and toxicity of conventional and pretargeted radioimmunotherapy in CD20-expressing human lymphoma xenografts

K Subbiah, DK Hamlin, JM Pagel… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Pretargeted radioimmunotherapy (RIT) using streptavidin (sAv)-conjugated antibodies
before radiolabeled-biotin is a promising approach to improve absorbed dose ratios and …

[HTML][HTML] 99mTc-labeled Rituximab for Imaging B Lymphocyte Infiltration in Inflammatory Autoimmune Disease Patients

G Malviya, KL Anzola, E Podesta, B Lagana… - Molecular imaging and …, 2012 - Springer
Purpose The rationale of the present study was to radiolabel rituximab with 99m-technetium
and to image B lymphocytes infiltration in the affected tissues of patients with chronic …

[HTML][HTML] Synthesis and Evaluation of 99mTc-Labelled Monoclonal Antibody 1D09C3 for Molecular Imaging of Major Histocompatibility Complex Class II Protein …

G Malviya, EFJ De Vries, RA Dierckx… - Molecular imaging and …, 2011 - Springer
Purpose It is known that major histocompatibility complex class II protein HLA-DR is highly
expressed in B-cell lymphomas and in a variety of autoimmune and inflammatory diseases …

Myeloablative 131I-tositumomab radioimmunotherapy in treating non-Hodgkin's lymphoma: comparison of dosimetry based on whole-body retention and dose to …

JG Rajendran, AK Gopal, DR Fisher… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Myeloablative radioimmunotherapy using 131I-tositumomab (anti-CD20) monoclonal
antibodies is an effective therapy for B-cell non-Hodgkin's lymphoma. The amount of …

High-dose 131I-tositumomab (anti-CD20) radioimmunotherapy for non-Hodgkin's lymphoma: adjusting radiation absorbed dose to actual organ volumes

JG Rajendran, DR Fisher, AK Gopal… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Radioimmunotherapy (RIT) using 131I-tositumomab has been used successfully to treat
relapsed or refractory B-cell non-Hodgkin's lymphoma (NHL). Our approach to treatment …

Pretargeted versus directly targeted radioimmunotherapy combined with anti-CD20 antibody consolidation therapy of non-Hodgkin lymphoma

RM Sharkey, H Karacay, CR Johnson… - Journal of Nuclear …, 2009 - Soc Nuclear Med
We determined whether therapeutic responses using a bispecific antibody that pretargeted
90Y-hapten-peptide radioimmunotherapy or a directly radiolabeled, humanized, 90Y-anti …

[PDF][PDF] Imaging B lymphocytes in autoimmune inflammatory diseases

V Iodice, B Lagana, C Lauri, G Capriotti… - The Quarterly Journal …, 2014 - researchgate.net
B cells arise from stem cells precursor and develop through a tightly regulated and selective
process that lead to the generation of different B cell populations such as transitional …

Cure of Micrometastatic B-Cell Lymphoma in a SCID Mouse Model Using 213Bi-Anti-CD20 Monoclonal Antibody

GT Havlena, NS Kapadia, P Huang… - Journal of Nuclear …, 2023 - Soc Nuclear Med
We studied the feasibility of using the α-emitting 213Bi-anti-CD20 therapy with direct
bioluminescent tracking of micrometastatic human B-cell lymphoma in a SCID mouse model …

99mTc-labelled rituximab, a new non-Hodgkin's lymphoma imaging agent: first clinical experience

TG Stopar, J Fettich, S Zver… - Nuclear Medicine …, 2008 - journals.lww.com
Objective This study was performed to explore the possibility of using 99m Tc-rituximab as
an imaging agent to assess expression of CD20 antigen in patients with B-cell non …