Dialkylamino-alkyl-benzamides possess an affinity for melanin, suggesting that labeling of
such benzamides with 18F could potentially produce melanin-targeted PET probes able to …

Introduction Melanoma is a highly malignant cutaneous tumor of melanin-producing cells.
MEL050 is a synthetic benzamide-derived molecule that specifically binds to melanin with …

The aim of this study was to evaluate the novel probe 18F-6-fluoro-N-[2-(diethylamino) ethyl]
pyridine-3-carboxamide (18F-MEL050) for the imaging of primary and metastatic melanoma …

Radiofluorinated benzamide and nicotinamide analogues are promising molecular probes
for the positron emission tomography (PET) imaging of melanoma. Compounds containing …

The efficacy of differing routes of administration of 18F-6-fluoro-N-[2-(diethylamino) ethyl]
pyridine-3-carboxamide (18F-MEL050), a new benzamide-based PET radiotracer for …

Purpose Radiolabelled benzamides are attractive candidates for targeting melanoma
because they bind to melanin and exhibit high tumour uptake and retention. 18 F-5-Fluoro-N …

Radiolabeled benzamides have been reported to be attractive agents for targeting
malignant melanoma as they bind melanin and display high accumulation in melanoma …

N-(2-(diethylamino)-ethyl)-18F-5-fluoropicolinamide (18F-P3BZA) is a radiotracer that
demonstrates high binding selectivity and affinity in melanoma. The aim of the present study …

Purpose Here, we report a new and rapid radiosynthesis of 18 FN-[2-(diethylamino) ethyl]-6-
fluoro-pyridine-3-carboxamide ([18 F] ICF01006), a molecule with a high specificity for …

PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as
a single fluorinated and iodinated melanin-targeting compound. METHODS: Studies were …