454 Objectives: The IMMUNE-AD study (NIH R01-AG022304) is investigating potential
mechanisms by which physical activity counteracts the negative effects of the APOE ε4 …

P1318 Introduction: Volumetric statistical amyloid burden has been used to distinguish
amyloid positive and amyloid negative patients with a z-score threshold.[Piper et al. 2014] …

This study evaluated performance of a commercially available standardized software
program for calculation of florbetapir PET standard uptake value ratios (SUVr) in comparison …

Accurate measurement of amyloid-b (Ab) PET tracer retention has become an increasingly
important feature of neuroimaging research in Alzheimer disease (AD). Although initial Ab …

PET amyloid imaging is increasingly used in research trials related to Alzheimer disease
and has potential as a quantitative biomarker. This study had 3 objectives: first, to describe a …

INTRODUCTION The Centiloid scale aims to harmonize amyloid beta (Aβ) positron
emission tomography (PET) measures across different analysis methods. As Centiloids were …

CONCLUSIONS♦ This randomised study supports the hypothesis that knowledge of amyloid
status as determined by florbetapir PET imaging impacts diagnosis and alters patient …

Purpose Several radiotracers that bind to fibrillar amyloid-beta in the brain have been
developed and used in various patient cohorts. This study aimed to investigate the …

P473 Introduction: The Centiloid scale is well established as a simple and highly useful
measure of brain amyloid burden. However, amyloid PET images contain spatial information …

2605 Introduction: Amyloid-β (Aβ) deposition is one of the earliest detectable brain changes
in Alzheimer's disease (AD) pathogenesis. In clinical practice, brain amyloid can be …