Preoperative characterization of thyroid nodules is challenging since thyroid scintigraphy
fails to distinguish between benign and malignant lesions. Galectin-3 (gal-3) is expressed in …

Background: The lack of facile methods for the specific characterization of malignant thyroid
nodules makes the diagnosis of thyroid cancer (TC) challenging. Due to its restricted …

Background The prevalence of thyroid nodules increases with age, average 4–7% for the
USA adult population, but it is much higher (19–67%) when sub-clinical nodules are …

Galectins (S-type lectins) are an evolutionarily-conserved family of lectin molecules, which
can be expressed intracellularly and in the extracellular matrix, as well. Galectins bind β …

The lack of a non-invasive test for malignant thyroid nodules makes the diagnosis of thyroid
cancer (TC) challenging. Human galectin-3 (hGal3) has emerged as a promising target for …

Introduction: Thyroid nodules are very common in the general population, most are benign,
and do not require any intervention. However, often a challenge exists in discriminating …

Galectin-3 (Gal-3), which has received significant recent attention for its utility as a
diagnostic marker for thyroid cancer, represents the most well-studied molecular candidate …

The high prevalence of thyroid nodules in the adult population and the relatively low
incidence of thyroid cancer make the preoperative identification of malignant lesions …

Fine-needle aspiration (FNA) is the most commonly used pre-operative technique for
diagnosis of malignant thyroid tumor. However, many benign lesions, with indeterminate …

Thyroid cancer is not very common, accounting for 1–2% of all cancers, with a population
incidence of about 0.004%. Currently, the ability to discriminate between follicular adenoma …