Tyrosine kinase receptors including vascular endothelial growth factor receptor (VEGFR)
have gained significant attention as pharmacologic targets. However, clinical evaluation of …

For solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing
response to therapy. Here we report the first example, to our knowledge, of 64Cu-labeled …

Purpose Noninvasive positron emission tomography (PET) imaging of vascular endothelial
growth factor receptor 2 (VEGFR-2) expression could be a valuable tool for evaluation of …

Vascular endothelial growth factor-A (VEGF-A) acts via 2 vascular endothelial growth factor
receptors, VEGFR-1 and VEGFR-2, that play important and distinct roles in tumor biology …

Several drugs targeting vascular endothelial growth factor (VEGF) and its receptors
(VEGFRs) are approved for cancer treatment. However, these drugs induce relatively …

The endothelin subtype-A (ETA) receptor is a member of a family of G-protein–coupled
receptors that plays a central role in vasoconstriction, cell proliferation, and hormone …

Overexpression of vascular endothelial growth factor (VEGF) and VEGF receptors (VEGFRs)
indicates poor prognosis for cancer patients in a variety of clinical studies. Our goal is to …

Purpose The aim of this study was to evaluate positron emission tomography (PET) imaging
with [68 Ga] NODAGA-c (RGDfK)([68 Ga] RGD), in comparison with 2-deoxy-2-[18 F] fluoro …

Imaging agents based on peptide probes have desirable pharmacokinetic properties
provided that they have high affinities for their target in vivo. An approach to improve a …

INTRODUCTION: VEGF receptors play a key role in angiogenesis and are important targets
for several approved and many experimental drugs. Imaging of VEGF receptor expression in …