An 18F-labeled PSMA ligand for PET/CT of prostate cancer: first-in-humans observational study and clinical experience with 18F-JK-PSMA-7 during the first year of …

F Dietlein, M Hohberg, C Kobe… - Journal of nuclear …, 2020 - Soc Nuclear Med
In preclinical trials, the recently developed tracer 2-methoxy-18F-DCFPyL (18F-JK-prostate-
specific membrane antigen [PSMA]-7) has shown favorable properties regarding clinical …

Intraindividual comparison of 18F-PSMA-1007 with renally excreted PSMA ligands for PSMA PET imaging in patients with relapsed prostate cancer

F Dietlein, C Kobe, M Hohberg… - Journal of nuclear …, 2020 - Soc Nuclear Med
18F-prostate-specific membrane antigen (PSMA)-1007 is excreted mainly through the liver.
We benchmarked the performance of 18F-PSMA-1007 against 3 renally excreted PSMA …

18F-PSMA-1007 PET/CT at 60 and 120 minutes in patients with prostate cancer: biodistribution, tumour detection and activity kinetics

K Rahbar, A Afshar-Oromieh, M Bögemann… - European journal of …, 2018 - Springer
Purpose PSMA-targeted PET in patients with prostate cancer (PCa) has a significant impact
on treatment decisions. By far the most frequently used PSMA ligand is 68 Ga-labelled …

The theranostic PSMA ligand PSMA-617 in the diagnosis of prostate cancer by PET/CT: biodistribution in humans, radiation dosimetry, and first evaluation of tumor …

A Afshar-Oromieh, H Hetzheim… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET imaging with the prostate-specific membrane antigen (PSMA)–targeted radioligand
68Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer …

[HTML][HTML] Diagnostic performance of 18F-PSMA-1007 PET/CT in patients with biochemical recurrent prostate cancer

K Rahbar, A Afshar-Oromieh, R Seifert… - European journal of …, 2018 - Springer
Purpose The introduction of ligands targeting prostate-specific membrane antigen (PSMA),
especially 68 Ga-PSMA-11, has changed the management of patients with prostate cancer …

[PDF][PDF] Matched-pair comparison of 68Ga-PSMA-11 and 18F-rhPSMA-7 PET/CT in patients with primary and biochemical recurrence of prostate cancer: Frequency of …

M Kroenke, L Mirzoyan, T Horn… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Radiohybrid prostate-specific membrane antigen (rhPSMA) ligands are a new class of
prostate cancer theranostic agents. 18F-rhPSMA-7 offers the advantages of 18F labeling …

[HTML][HTML] High detection rate in [18F]PSMA-1007 PET: interim results focusing on biochemical recurrence in prostate cancer patients

T Watabe, M Uemura, F Soeda, S Naka, T Ujike… - Annals of Nuclear …, 2021 - Springer
Objective 18 F-labeled prostate-specific membrane antigen (PSMA) ligand,[18 F] PSMA-
1007, has the benefit of a higher synthetic yield and minimal excretion in the urine. High …

Discovery of 18F-JK-PSMA-7, a PET probe for the detection of small PSMA-positive lesions

BD Zlatopolskiy, H Endepols, P Krapf… - Journal of nuclear …, 2019 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA), expressed by most prostate carcinomas (PCa),
is a promising target for PCa imaging. The application of PSMA-specific 18F-labeled PET …

Preliminary Evaluation of 68Ga-P16-093, a PET Radiotracer Targeting Prostate-Specific Membrane Antigen in Prostate Cancer

H Lee, JS Scheuermann, AJ Young, RK Doot… - Molecular Imaging and …, 2022 - Springer
Purpose Prostate-specific membrane antigen (PSMA) is a promising molecular target for
imaging of prostate adenocarcinoma. 68Ga-P16-093, a small molecule PSMA ligand …

[HTML][HTML] Biodistribution and radiation dosimetry of [18F]-JK-PSMA-7 as a novel prostate-specific membrane antigen-specific ligand for PET/CT imaging of prostate …

M Hohberg, C Kobe, P Krapf, P Täger, J Hammes… - EJNMMI research, 2019 - Springer
Aim We investigated the whole-body distribution and the radiation dosimetry of [18 F]-JK-
PSMA-7, a novel 18 F-labeled PSMA-ligand for PET/CT imaging of prostate cancer. Methods …