Dynamic amyloid PET: relationships to 18F-flortaucipir tau PET measures
Measuring amyloid and predicting tau status using a single amyloid PET study would be
valuable for assessing brain AD pathophysiology. We hypothesized that early-frame amyloid …
valuable for assessing brain AD pathophysiology. We hypothesized that early-frame amyloid …
Optimizing longitudinal amyloid-β PET measurement: the challenges of intensity normalization
SM Landau - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
Accurate measurement of amyloid-b (Ab) PET tracer retention has become an increasingly
important feature of neuroimaging research in Alzheimer disease (AD). Although initial Ab …
important feature of neuroimaging research in Alzheimer disease (AD). Although initial Ab …
Comparison of regional flortaucipir PET SUVr values to quantitative tau histology and quantitative tau immunoassay in patients with Alzheimer's disease pathology: a …
629 Objectives: PET tracers for tau pathology in Alzheimer's disease (AD) are of increasing
interest as diagnostics and as markers of disease severity. However, there have been few …
interest as diagnostics and as markers of disease severity. However, there have been few …
One-stop shop: 18F-flortaucipir PET differentiates amyloid-positive and-negative forms of neurodegenerative diseases
J Hammes, GN Bischof, KP Bohn, Ö Onur… - Journal of nuclear …, 2021 - Soc Nuclear Med
Tau protein aggregations are a hallmark of amyloid-associated Alzheimer disease and
some forms of non–amyloid-associated frontotemporal lobar degeneration. In recent years …
some forms of non–amyloid-associated frontotemporal lobar degeneration. In recent years …
Tau PET imaging in neurodegenerative disorders
C Groot, S Villeneuve, R Smith… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The advent of PET ligands that bind tau pathology has enabled the quantification and
visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong …
visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong …
[HTML][HTML] Assessment of perfusion deficit with early phases of [18F]PI-2620 tau-PET versus [18F]flutemetamol-amyloid-PET recordings
F Völter, L Beyer, F Eckenweber, M Scheifele… - European journal of …, 2023 - Springer
Purpose Characteristic features of amyloid-PET (A), tau-PET (T), and FDG-PET (N) can
serve for the A/T/N classification of neurodegenerative diseases. Recent studies showed …
serve for the A/T/N classification of neurodegenerative diseases. Recent studies showed …
[HTML][HTML] Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging
Purpose Several radiotracers that bind to fibrillar amyloid-beta in the brain have been
developed and used in various patient cohorts. This study aimed to investigate the …
developed and used in various patient cohorts. This study aimed to investigate the …
TauIQ: A canonical image based algorithm to quantify tau PET scans
A Whittington, RN Gunn… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Recently, AmyloidIQ was introduced as a new canonical image-based algorithm to quantify
amyloid PET scans and demonstrated increased power over traditional SUV ratio (SUVR) …
amyloid PET scans and demonstrated increased power over traditional SUV ratio (SUVR) …
[HTML][HTML] The spatial extent of tauopathy on [18F] MK-6240 tau PET shows stronger association with cognitive performances than the standard uptake value ratio in …
T Gérard, L Colmant, V Malotaux, Y Salman… - European Journal of …, 2024 - Springer
Purpose [18 F] MK-6240, a second-generation tau PET tracer, is increasingly used for the
detection and the quantification of in vivo cerebral tauopathy in Alzheimer's disease (AD) …
detection and the quantification of in vivo cerebral tauopathy in Alzheimer's disease (AD) …
Feasibility of 18F-THK5351 PET quantitation using the Centiloid scale
T Yamao, K Miwa, H Matsuda, G Akamatsu… - 2019 - Soc Nuclear Med
1182 Objectives: Tau PET imaging has played a key role in assessing tau pathology
associated with Alzheimer disease (AD) in vivo. Standard methods of evaluation are …
associated with Alzheimer disease (AD) in vivo. Standard methods of evaluation are …
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