Personalized dosimetry with intensification using 90Y-loaded glass microsphere radioembolization induces prolonged overall survival in hepatocellular carcinoma …

E Garin, Y Rolland, J Edeline, N Icard… - Journal of Nuclear …, 2015 - Soc Nuclear Med
The objective of this study was to evaluate the response rate and survival of hepatocellular
carcinoma portal vein thrombosis (PVT) patients treated with 90Y-loaded glass …

Dosimetry based on 99mTc-macroaggregated albumin SPECT/CT accurately predicts tumor response and survival in hepatocellular carcinoma patients treated with …

E Garin, L Lenoir, Y Rolland, J Edeline… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Radioembolization of liver cancers using 90Y-loaded microspheres is experiencing more
widespread use. However, few data are available concerning the doses delivered to the …

Radioembolization of hepatocarcinoma with 90Y glass microspheres: development of an individualized treatment planning strategy based on dosimetry and …

C Chiesa, M Mira, M Maccauro, C Spreafico… - European journal of …, 2015 - Springer
Purpose The aim of this study was to optimize the dosimetric approach and to review the
absorbed doses delivered, taking into account radiobiology, in order to identify the optimal …

90Y radioembolization for locally advanced hepatocellular carcinoma with portal vein thrombosis: long-term outcomes in a 185-patient cohort

N Abouchaleh, A Gabr, R Ali, A Al Asadi… - Journal of Nuclear …, 2018 - Soc Nuclear Med
We report survival outcomes for patients with advanced-stage hepatocellular carcinoma
(HCC) with portal vein thrombosis (PVT) treated with 90Y radioembolization. Methods: With …

90Y-loaded microsphere SIRT of HCC patients with portal vein thrombosis: high clinical impact of 99mTc-MAA SPECT/CT-based dosimetry

E Garin, Y Rolland, J Edeline - Seminars in Nuclear Medicine, 2019 - Elsevier
Radioembolization with 90 Y-loaded microspheres based on classical prescription methods
is increasingly applied to hepatocellular carcinoma (HCC) patients with portal vein …

Radioembolization with use of yttrium-90 resin microspheres in patients with hepatocellular carcinoma and portal vein thrombosis

M Iñarrairaegui, KG Thurston, JI Bilbao… - Journal of Vascular and …, 2010 - Elsevier
PURPOSE: Intraarterial delivery of yttrium-90 (90Y)–bound microspheres (ie,
radioembolization) is a promising treatment for hepatocellular carcinoma (HCC). An early …

[HTML][HTML] Boosted selective internal radiation therapy with 90Y-loaded glass microspheres (B-SIRT) for hepatocellular carcinoma patients: a new personalized …

E Garin, L Lenoir, J Edeline, S Laffont… - European journal of …, 2013 - Springer
Purpose To evaluate the impact of dosimetry based on MAA SPECT/CT for the prediction of
response, toxicity and survival, and for treatment planning in patients with hepatocellular …

Hepatocellular carcinoma tumor dose response after 90Y-radioembolization with glass microspheres using 90Y-SPECT/CT-based voxel dosimetry

SC Kappadath, J Mikell, A Balagopal… - International Journal of …, 2018 - Elsevier
Purpose To investigate hepatocellular carcinoma tumor dose-response characteristics
based on voxel-level absorbed doses (D) and biological effective doses (BED) using …

Radioembolization for hepatocellular carcinoma with portal vein thrombosis: impact of liver function on systemic treatment options at disease progression

K Memon, L Kulik, RJ Lewandowski, MF Mulcahy… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: Yttrium-90 (90Y) radioembolization is a microembolic procedure.
Hence, it is commonly used in hepatocellular carcinoma (HCC) patients with portal venous …

Radioembolization of hepatocarcinoma with 90Y glass microspheres: treatment optimization using the dose-toxicity relationship

C Chiesa, M Mira, S Bhoori, G Bormolini… - European Journal of …, 2020 - Springer
Aim Transarterial radioembolization (TARE) is, by all standards, a radiation therapy. As
such, according to Euratom Directive 2013/59, it should be optimized by a thorough …