A standardized light-emitting diode device for photoimmunotherapy
E de Boer, JM Warram, E Hartmans… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Antibody-based photodynamic therapy—photoimmunotherapy (PIT)—is an ideal modality to
improve cancer treatment because of its selective and tumor-specific mode of therapy …
improve cancer treatment because of its selective and tumor-specific mode of therapy …
[HTML][HTML] The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity
T Nakajima, K Sato, H Hanaoka, R Watanabe… - BMC cancer, 2014 - Springer
Background Photoimmunotherapy (PIT) is a highly cell-selective cancer therapy, which
employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700). Once …
employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700). Once …
[HTML][HTML] Implantable wireless powered light emitting diode (LED) for near-infrared photoimmunotherapy: device development and experimental assessment in vitro …
K Nakajima, T Kimura, H Takakura, Y Yoshikawa… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Purpose The aim of this study was to develop and assess a novel implantable, wireless-
powered, light-emitting diode (LED) for near-infrared photoimmunotherapy (NIR-PIT). NIR …
powered, light-emitting diode (LED) for near-infrared photoimmunotherapy (NIR-PIT). NIR …
[HTML][HTML] Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies
N Shirasu, H Shibaguchi, H Yamada, M Kuroki… - Cancer Cell …, 2019 - Springer
Background Photoimmunotherapy (PIT) employing antibody-photosensitizer conjugates is a
promising treatment for cancer. However, the fixed antigen specificity severely limits the …
promising treatment for cancer. However, the fixed antigen specificity severely limits the …
Near-infrared theranostic photoimmunotherapy (PIT): repeated exposure of light enhances the effect of immunoconjugate
M Mitsunaga, T Nakajima, K Sano… - Bioconjugate …, 2012 - ACS Publications
Armed antibody-based targeted molecular therapies offer the possibility of effective tumor
control with a minimum of side effects. Photoimmunotherapy (PIT) employs a monoclonal …
control with a minimum of side effects. Photoimmunotherapy (PIT) employs a monoclonal …
[HTML][HTML] Applying near-infrared photoimmunotherapy to B-cell lymphoma: comparative evaluation with radioimmunotherapy in tumor xenografts
YD Heryanto, H Hanaoka, T Nakajima… - Annals of Nuclear …, 2017 - Springer
Objective Radioimmunotherapy (RIT) has proven effective for patients with relapsed and
refractory lymphoma. However, new types of therapy are strongly desired as B-cell …
refractory lymphoma. However, new types of therapy are strongly desired as B-cell …
[HTML][HTML] Interstitial near-infrared photoimmunotherapy: effective treatment areas and light doses needed for use with fiber optic diffusers
S Okuyama, T Nagaya, K Sato, F Ogata, Y Maruoka… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Near-infrared photoimmunotherapy (NIR-PIT), a promising cancer therapy utilizing an
antibody-photoabsorber conjugate (APC) and NIR light, which induces rapid necrotic cell …
antibody-photoabsorber conjugate (APC) and NIR light, which induces rapid necrotic cell …
[HTML][HTML] The effect of subcellular localization on the efficiency of EGFR-targeted VHH photosensitizer conjugates
SAM van Lith, D van den Brand, R Wallbrecher… - European Journal of …, 2018 - Elsevier
Photodynamic therapy (PDT) is an emerging method to treat light-accessible malignancies.
To increase specificity and allow dose reduction, conjugates of photosensitizers (PS) with …
To increase specificity and allow dose reduction, conjugates of photosensitizers (PS) with …
[HTML][HTML] Molecular targeted photoimmunotherapy for HER2-positive human gastric cancer in combination with chemotherapy results in improved treatment outcomes …
K Ito, M Mitsunaga, S Arihiro, M Saruta, M Matsuoka… - BMC cancer, 2016 - Springer
Background Photoimmunotherapy (PIT) is a novel type of molecular optical imaging-guided
cancer phototherapy based on a monoclonal antibody conjugated to a photosensitizer …
cancer phototherapy based on a monoclonal antibody conjugated to a photosensitizer …
Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules
M Mitsunaga, M Ogawa, N Kosaka, LT Rosenblum… - Nature medicine, 2011 - nature.com
Three major modes of cancer therapy (surgery, radiation and chemotherapy) are the
mainstay of modern oncologic therapy. To minimize the side effects of these therapies …
mainstay of modern oncologic therapy. To minimize the side effects of these therapies …