Renal uptake of radiolabeled octreotide in human subjects is efficiently inhibited by succinylated gelatin
E Vegt, JFM Wetzels, FGM Russel… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Peptide receptor–mediated radiotherapy of neuroendocrine and other somatostatin receptor–
positive tumors with radiolabeled somatostatin analogs has been applied in several …
positive tumors with radiolabeled somatostatin analogs has been applied in several …
Gelatin-based plasma expander effectively reduces renal uptake of 111In-octreotide in mice and rats
JEM van Eerd, E Vegt, JFM Wetzels… - Journal of nuclear …, 2006 - Soc Nuclear Med
111In-Diethylenetriaminepentaacetic acid-octreotide generally is used for the scintigraphic
imaging of neuroendocrine and other somatostatin receptor–positive tumors. On the basis of …
imaging of neuroendocrine and other somatostatin receptor–positive tumors. On the basis of …
Safe and effective inhibition of renal uptake of radiolabelled octreotide by a combination of lysine and arginine
EJ Rolleman, R Valkema, M De Jong, PP Kooij… - European journal of …, 2003 - Springer
As scintigraphy with [111 In-DTPA 0] octreotide has become a standard technique in
analysing somatostatin receptor-receptor positive lesions such as neuroendocrine tumours …
analysing somatostatin receptor-receptor positive lesions such as neuroendocrine tumours …
Kidney protection during peptide receptor radionuclide therapy with somatostatin analogues
EJ Rolleman, M Melis, R Valkema, OC Boerman… - European journal of …, 2010 - Springer
This review focuses on the present status of kidney protection during peptide receptor
radionuclide therapy (PRRT) using radiolabelled somatostatin analogues. This treatment …
radionuclide therapy (PRRT) using radiolabelled somatostatin analogues. This treatment …
[HTML][HTML] Dose-response effect of Gelofusine on renal uptake and retention of radiolabelled octreotate in rats with CA20948 tumours
M Melis, M Bijster, M de Visser… - European journal of …, 2009 - Springer
Purpose Peptide receptor radionuclide therapy using β-emitting radiolabelled somatostatin
analogues like DOTA, Tyr 3-octreotate shows beneficial results in patients suffering from …
analogues like DOTA, Tyr 3-octreotate shows beneficial results in patients suffering from …
Renal toxicity of radiolabeled peptides and antibody fragments: mechanisms, impact on radionuclide therapy, and strategies for prevention
E Vegt, M de Jong, JFM Wetzels… - Journal of nuclear …, 2010 - Soc Nuclear Med
Peptide-receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs such
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …
Molecular imaging of reduced renal uptake of radiolabelled [DOTA0, Tyr3] octreotate by the combination of lysine and Gelofusine in rats
EJ Rolleman, BF Bernard… - Nuklearmedizin …, 2008 - thieme-connect.com
Aim: In peptide receptor radionuclide therapy (PRRT) using radiolabelled somatostatin
analogues, kidney uptake of radiolabelled compound is the major dose-limiting factor. We …
analogues, kidney uptake of radiolabelled compound is the major dose-limiting factor. We …
Reduction of renal uptake of radiolabeled octreotate by amifostine coadministration
M Melis, R Valkema, EP Krenning… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Megalin-mediated renal retention of radiolabeled somatostatin analogs may lead to
nephrotoxicity during peptide receptor radionuclide therapy (PRRT). The cytoprotective …
nephrotoxicity during peptide receptor radionuclide therapy (PRRT). The cytoprotective …
Metabolic effects of amino acid solutions infused for renal protection during therapy with radiolabelled somatostatin analogues
R Barone, S Pauwels, J De Camps… - Nephrology Dialysis …, 2004 - academic.oup.com
Background. Infusion of amino acids (AAs) can reduce renal uptake of radiolabelled
somatostatin analogues resulting in a lower kidney exposure during peptide radiotherapy of …
somatostatin analogues resulting in a lower kidney exposure during peptide radiotherapy of …
[HTML][HTML] Somatostatin receptor subtype 2-mediated uptake of radiolabelled somatostatin analogues in the human kidney
EJ Rolleman, PPM Kooij, WW de Herder… - European journal of …, 2007 - Springer
Purpose Renal irradiation is a dose-limiting factor in peptide receptor radionuclide therapy
using radiolabelled somatostatin analogues. This irradiation is mainly caused by …
using radiolabelled somatostatin analogues. This irradiation is mainly caused by …
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