3005 Background: One of the unique strengths of radiation medicine is its ability to induce
cytotoxicity, while an associated challenge is its unintended bystander effects. These …

Simple Summary Cerium oxide nanoparticles (nanoceria) influence its environment by
donating or accepting electrons readily. We investigated nanoceria's ability to modify the …

Abstract 754 Background: Selective or preferential protection of normal tissues is an
attractive and potential approach to improve radiotherapy of cancer patients. Currently, we …

Results Cell viability and cell death assays showed that CeO 2 protected 99% of normal
breast cells from radiation-induced cell death (RICD), whereas breast cancer cells were not …

At the onset of radiation exposure, free radicals are formed through ionizing reactions that
are then capable of destroying normal tissues. While cells release a level of protective …

T24 Introduction: Both acute and delayed cutaneous responses occur following injury from
ionizing radiation. Currently there are no FDA approved preventive measures that would …

Low-dose ionizing radiations are commonly utilized in medical centers for diagnostic
imaging procedures. Unfortunately, the absorption of ionizing radiation generates reactive …

Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells
while minimizing damage to healthy cells and new methods that can accomplish this goal …

Optimal distribution of cerium oxide nanoparticles (CONPs) or nanoceria can have a
significant impact on their cytotoxicity, cellular uptake, and radioprotection effects. In this …

Cerium oxide nanomaterials are known to absorb ionizing radiation energy, as well as to
neutralize free radicals in solution, by undergoing redox changes. We, therefore, proposed …