Quantification of 18F-fluorocholine kinetics in patients with prostate cancer

EE Verwer, DE Oprea-Lager… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Choline kinase is upregulated in prostate cancer, resulting in increased 18F-
fluoromethylcholine uptake. This study used pharmacokinetic modeling to validate the use of …

Repeatability of quantitative 18F-fluoromethylcholine PET/CT studies in prostate cancer

DE Oprea-Lager, G Kramer… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Repeatable quantification is essential when using 18F-fluoromethylcholine PET/CT to
monitor treatment response in prostate cancer. It has been shown that SUV normalized to …

Simplified methods for quantification of 18F-DCFPyL uptake in patients with prostate cancer

BHE Jansen, M Yaqub, J Voortman… - Journal of nuclear …, 2019 - Soc Nuclear Med
Radiolabeled prostate-specific membrane antigen (PSMA) PET has demonstrated
promising results for prostate cancer (PCa) imaging. Quantification of PSMA radiotracer …

11C-choline pharmacokinetics in recurrent prostate cancer

M Grkovski, K Gharzeddine, P Sawan… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The aim of this study was to investigate the value of pharmacokinetic modeling for
quantifying 11C-choline uptake in patients with recurrent prostate cancer. Methods: In total …

[HTML][HTML] Quantitative 18F-fluorocholine positron emission tomography for prostate cancer: correlation between kinetic parameters and Gleason scoring

JD Schaefferkoetter, Z Wang, MC Stephenson, S Roy… - EJNMMI research, 2017 - Springer
Background The use of radiolabeled choline as a positron emission tomography (PET)
agent for imaging primary tumors in the prostate has been evaluated extensively over the …

A compartmental model for biokinetics and dosimetry of 18F-choline in prostate cancer patients

A Giussani, T Janzen, H Uusijärvi-Lizana… - Journal of Nuclear …, 2012 - Soc Nuclear Med
PET with 18F-choline (18F-FCH) is used in the diagnosis of prostate cancer and its
recurrences. In this work, biodistribution data from a recent study conducted at Skåne …

3D prostate gland uptake of 18F-choline-association with overall survival in patients with hormone-naïve prostate cancer

M Sadik, E Polymeri, R Kaboteh, O Enqvist, F Fejne… - 2017 - Soc Nuclear Med
544 Objectives: To develop a completely automated method to quantify prostate gland
uptake of 18F-choline in PET/CT images and to study the relationship between this …

Comparison of choline influx from dynamic 18F-Choline PET/CT and clinicopathological parameters in prostate cancer initial assessment

X Palard-Novello, AL Blin, D Bourhis, E Garin… - Annals of Nuclear …, 2018 - Springer
Aim The aim of the study was to compare the kinetic analysis of 18 F-labeled choline (FCH)
uptake with static analysis and clinicopathological parameters in patients with newly …

Furosemide diminishes 18F-fluoroethylcholine uptake in prostate cancer in vivo

HC Rischke, T Beck, W Vach, G Wieser… - European journal of …, 2014 - Springer
Abstract Purpose 18 F-Fluoroethylcholine (18 F-FECh) is excreted via the urinary system
with high activity accumulation in the urinary bladder. Furosemide and oral hydration can be …

Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer

GM Kramer, M Yaqub, HA Vargas… - Journal of Nuclear …, 2019 - Soc Nuclear Med
18F-fluorodihydrotestosterone (18F-FDHT) PET/CT potentially provides a noninvasive
method for assessment of androgen receptor expression in patients with metastatic …