[PDF][PDF] Generator-produced copper-62-PTSM as a myocardial PET perfusion tracer compared with nitrogen-13-ammonia

E Tadamura, N Tamaki, H Okazawa… - Journal of Nuclear …, 1996 - Soc Nuclear Med
The purpose of this study was to determine the suitability of 62Cupyruvaldehyde bis (N4-
methylthiosemicarbazone) f2Cu-PTSM) for es timating myocardial blood flow (MBF) over a …

[PDF][PDF] Regional myocardial perfusion assessed with generator-produced copper-62-PTSM and PET

P Herrero, JJ Hartman, MA Green… - Journal of Nuclear …, 1996 - Soc Nuclear Med
We have previously demonstrated that myocardial perfusion can be estimated accurately in
experimental animals with the generatorproduced positron-emitting tracer, 62Cu …

What is the best approach to quantify myocardial blood flow with pet?

GD Hutchins - Journal of Nuclear Medicine, 2001 - Soc Nuclear Med
In recent years, many approaches have been developed in an attempt to optimize the
quantitative measurement of myocardial blood flow (MBF) using agents labeled with …

[PDF][PDF] Human biodistribution and dosimetry of the PET perfusion agent copper-62-PTSM

TR Wallhaus, J Lacy, J Whang, MA Green… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Copper-62-pyruvaldehyde bis (N4-methyl) thiosemicarbazone (PTSM) has been proposed
as a generator-produced radiopharmaceutical for perfusion imaging using PET. Several …

Copper-62-pyruvaldehyde bis (N4-methyl-thiosemicarbazone) PET imaging in the detection of coronary artery disease in humans

TR Wallhaus, J Lacy, R Stewart, J Bianco… - Journal of Nuclear …, 2001 - Elsevier
Background. Copper-62 (II)-pyruvaldehyde bis (N4-methyl-thiosemicarbazone)(PTSM) has
been proposed for cardiac imaging with positron emission tomography (PET). This study …

Tissue blood flow estimation with copper (II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone) and PET.

H Young, P Carnochan, J Zweit, J Babich… - Journal of Nuclear …, 1994 - europepmc.org
Copper (II)-pyruvaldehyde bis (N-4-methylthiosemicarbazone)(Cu-PTSM) labelled with
62Cu or 64Cu is currently under investigation as a radiotracer for imaging the distribution of …

Measurement of myocardial blood flow with PET using 1-11C-acetate

RR Sciacca, O Akinboboye, RL Chou… - Journal of Nuclear …, 2001 - Soc Nuclear Med
11C-acetate has been used extensively for the noninvasive assessment of myocardial
oxygen consumption and viability with PET. The use of early uptake of acetate by the heart …

Promising new 18F-labeled tracers for PET myocardial perfusion imaging

RC Brunken - Journal of Nuclear Medicine, 2015 - Soc Nuclear Med
Myocardial perfusion imaging with PET offers several advantages over SPECT for the
detection and characterization of coronary artery disease. With PET, individual tissue …

Effect of reconstruction algorithms on myocardial blood flow measurement with 13N-ammonia PET

GP Chen, KR Branch, AM Alessio, P Pham… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Filtered backprojection (FBP) is the traditional method for 13N-NH3 PET studies. Ordered-
subsets expectation maximization (OSEM) is popular for PET studies because of better …

Assessment of myocardial perfusion by dynamic N-13 ammonia PET imaging: comparison of 2 tracer kinetic models

A Khorsand, S Graf, C Pirich, O Muzik, K Kletter… - Journal of nuclear …, 2005 - Springer
Background Measurement of myocardial blood flow (MBF) by dynamic nitrogen 13 ammonia
(NH3) positron emission tomography (PET) uses tracer kinetic modeling to analyze time …