To characterize better the local brain functions of conscious rhesus macaques, we
developed automated image analysis techniques for monkey PET images, examined the …

Because preclinical imaging offers challenges and opportunities, we set out to investigate
and optimize image processing techniques to measure changes in mouse brain metabolism …

To aid in the analysis of rhesus macaque brain images, we aligned digitized anatomical
regions from the widely used atlas of Paxinos et al. to a published magnetic resonance …

Rodent models and genetically altered mice have recently become available to study many
human diseases. A sensitive and accurate PET scanner for small animals would be useful to …

Automated voxel-based or predefined volume-of-interest (VOI) analysis of rodent small-
animal PET data is necessary for optimal use of information because the number of …

Methods The PET atlas was constructed from a high-resolution [18F] fluorodeoxyglucose
(FDG) image set of a normal volunteer (a 41-yr-old woman). The image set was reoriented …

U/D@ O. OLJR= O. O77242 13.00 to minimize variability in the data included administration
of a standardized non-ketogenic breakfast followed by fasting until after the scan, and …

Identification of small nuclei in the brain by PET has been limited by the spatial resolution of
conventional scanners. The new detector technology and advanced signal analysis of a …

The anatomy of the thalamus and its connectivity with surrounding areas are known.
Localized metabolic activities at the thalamic substructural level have not been measured in …

Cerebral glucose metabolism has been used as a marker of cerebral maturation and
neuroplasticity. In studies addressing these issues in young non-human primates …