Potential use of indium-111-labeled polymorphonuclear leukocytes for the detection of lung microvascular injury.

DK Das, H Steinberg, D Bandyopadhyay… - Journal of Nuclear …, 1988 - europepmc.org
The early stages of microvascular injury are often difficult to detect due to the lack of a
suitable marker to assess such an injury. We utilized the well known phenomenon of …

Role of polymorphonuclear leukocytes in hyperoxic lung injury. Prevention of neutrophil influx into the lung endothelium during oxygen exposure by ibuprofen.

DK Das, D Bandyopadhyay, S Hoory… - Biomedica Biochimica …, 1988 - europepmc.org
The present study examines the role of PMN in hyperoxic lung injury using a nonsteroidal
anti-inflammatory drug, ibuprofen. New Zealand white rabbits were exposed to 100 …

Comparison of indium-111-tropolone and indium-111-oxine as neutrophil-labeling agent for noninvasive detection of lung injury

DK Das, D Bandyopadhyay, S Hoory… - Second colloquium in …, 1986 - inis.iaea.org
[en] The lung injury resulting from 100% oxygen exposure is associated with an influx of
polymorphonuclear leukocytes (PMNs) into the lung. PMNs labeled with a suitable gamma …

Neutrophil kinetics in O2-exposed rabbits

H Steinberg, DK Das, JM Cerreta… - Journal of applied …, 1986 - journals.physiology.org
Hyperoxic injury results in an influx of polymorphonuclear leukocytes (PMN) into the lung. To
better understand the role of the PMN in this injury, kinetic studies were used to assess the …

Do indium 111-labeled polymorphonuclear leukocytes detect neutrophil-prominent, fibrosing lung disease in rats?

JH Williams, TM Hartman, J Lichter… - The Journal of …, 1987 - translationalres.com
The role of polymorphonuclear leukocytes ((PMNs) in fibrotic lung disease remains poorly
defined, but PMN prominence may predict a poor response to therapy in some patients. The …

Neutrophil activation and tissue neutrophil sequestration in a rat model of thermal injury

JF Hansbrough, T Wikström, M Braide… - Journal of Surgical …, 1996 - Elsevier
Neutrophil (PMN) deposition in tissues (leukosequestration) after shock may produce local
tissue injury from proteases and oxygen intermediaries which are released from …

Polymorphonuclear leukocytes released from the bone marrow preferentially sequester in lung microvessels

SF Van Eeden, Y Kitagawa, ME Klut… - …, 1997 - Wiley Online Library
Objective: A hallmark of the systemic response to an inflammatory stimulus is the release of
polymorphonuclear leukocytes (PMNs) from the bone marrow. This study was designed to …

[CITATION][C] Leucocytes and pulmonary microvascular injury

NC Staub, EL Schultz… - Annals of the New York …, 1982 - Wiley Online Library
Indirect injury to the lung's endothelial barrier due to interaction between physical and
chemical agents with elements in circulating blood is receiving increased attention since it …

[PDF][PDF] Is lung sequestration of indium-111-labeled granulocytes organ specific?

JH Williams, AF Wilson, KM Moser - Journal of nuclear medicine, 1989 - Soc Nuclear Med
Is Lung Sequestration of Indium- 111-Labeled Page 1 olymorphonuclear leukocytes (PMN)
labeled with indium-i 11(In-PMN) are utilized clinically to identify inflammatory processes, and …

Mediation of lung neutrophil uptake after endotoxin by CD18-integrin-dependent and-independent mechanisms

BK McCandless, RP Kaufman Jr… - American Journal …, 1994 - journals.physiology.org
We studied polymorphonuclear neutrophil (PMN) uptake in lungs of endotoxemic rabbits
using 111In-labeled PMN and isotope imaging by gamma scintigraphy. Rabbits were …