Abnormalities of norepinephrine uptake have been found to reflect impairment in adrenergic
nerve function that has influenced the cardiac outcome of patients with heart failure. The aim …

with 123l—MIBG in the Failing Human Heart Page 1 Sympathetic Nerve Alterations Assessed
with 123l—MIBG in the Failing Human Heart Pascal Merlet. Frédéric Pottillart. Jean—Lac …

The autonomic nervous system plays an important role in the human heart. Activation of the
cardiac sympathetic nerve system is a cardinal pathophysiological abnormality associated …

OBJECTIVES.: This study was undertaken to assess myocardial adrenergic activity using
iodine-123 metaiodobenzylguanidine (MIBG) imaging in patients with heart failure …

In chronic heart failure, elevated plasma norepinephrine (NE) levels and a disparity between
the neuronal release and the effective reuptake of NE lead to an increased concentration of …

Abnormalities of myocardial sympathetic nerve function were reported in congestive heart
failure (CHF). To assess myocardial sympathetic nerve function, we obtained …

Background ICD in primary prevention reduced mortality in patients with heart failure (HF);
however, in about 80% of the ICD recipients an event requiring a device intervention will …

Summary Background: Iodine 123‐metaiodobenzylguanidine (MIBG) imaging has been
used to assess cardiac sympathetic nerve abnormalities. To determine the role of MIBG …

The purpose of this study was to evaluate whether or not cardiac sympathetic nerve activity,
using 123 I-meta-iodobenzylguanidine (123 I-MIBG) imaging, and cardiac natriuretic …

Simultaneous assessment of regional adrenergic activity and perfusion with 123 I-meta-
iodobenzylguanidine (123 I-MIBG) and 201 Tl in various organs was performed in 13 …