Hypertension Increases Cerebral 6-18F-Fluorodopa–Derived Radioactivity
DS Goldstein, C Holmes, LT Sewell… - Journal of Nuclear …, 2009 - Soc Nuclear Med
6-18F-fluorodopa PET depicts the striatal dopaminergic lesion characterizing Parkinson
disease (PD); however, striatal uptake of 6-18F-fluorodopa–derived radioactivity can be …
disease (PD); however, striatal uptake of 6-18F-fluorodopa–derived radioactivity can be …
Simple ratio analysis of 18F-fluorodopa uptake in striatal subregions separates patients with early Parkinson disease from healthy controls
P Jokinen, H Helenius, E Rauhala… - Journal of Nuclear …, 2009 - Soc Nuclear Med
6-18F-fluoro-l-dopa (18F-FDOPA) is widely used to investigate dopaminergic hypofunction,
for instance, in Parkinson disease (PD). Conventionally, a 90-min scan with either a …
for instance, in Parkinson disease (PD). Conventionally, a 90-min scan with either a …
Functional analysis of 18F-DOPA PET for the diagnosis of Parkinson's disease
S Chen, YL Leung, T Cheng, KN Wong, C Ho - 2012 - Soc Nuclear Med
1905 Objectives 18F-DOPA PET is more useful than 18F-FDG in diagnosis of Parkinson9s
disease (PD). However, upregulation of decarboxylase enzyme in some early PD may …
disease (PD). However, upregulation of decarboxylase enzyme in some early PD may …
Comparative analysis of striatal FDOPA uptake in Parkinson's disease: ratio method versus graphical approach
V Dhawan, Y Ma, V Pillai, P Spetsieris… - Journal of Nuclear …, 2002 - Soc Nuclear Med
Striatal-to-occipital ratio (SOR) and influx constant Kiocc are commonly used as analytic
parameters in l-3, 4-dihydroxy-6-18F-fluorophenylalanine (FDOPA) PET studies. Both have …
parameters in l-3, 4-dihydroxy-6-18F-fluorophenylalanine (FDOPA) PET studies. Both have …
[HTML][HTML] [18F] FDOPA PET may confirm the clinical diagnosis of Parkinson's disease by imaging the nigro-striatal pathway and the sympathetic cardiac innervation …
J Kuten, A Linevitz, H Lerman, N Freedman… - Journal of Integrative …, 2020 - imrpress.com
Autonomic involvement, including cardiac denervation, may precede the motor symptoms of
Parkinson's disease by several years. L-3, 4-dihydroxy-6-[18F] fluoro-phenylalanine is a …
Parkinson's disease by several years. L-3, 4-dihydroxy-6-[18F] fluoro-phenylalanine is a …
FluoroDOPA PET shows the nondopaminergic as well as dopaminergic destinations of levodopa
WD Brown, MD Taylor, AD Roberts, TR Oakes… - Neurology, 1999 - AAN Enterprises
Objective: To evaluate the visible and quantitative anatomic distribution of fluorine-18–
labeled l-DOPA in the healthy human brain, to thereby expand the understanding of …
labeled l-DOPA in the healthy human brain, to thereby expand the understanding of …
Increased frontal [18F]fluorodopa uptake in early Parkinson's disease: sex differences in the prefrontal cortex
V Kaasinen, E Nurmi, A Brück, O Eskola, J Bergman… - Brain, 2001 - academic.oup.com
Previous imaging studies in Parkinson's disease have focused mainly on the striatum, a
region with very high dopaminergic activity. Using modern high-sensitivity 3D [18F] …
region with very high dopaminergic activity. Using modern high-sensitivity 3D [18F] …
Cognitive impairment and the brain dopaminergic system in Parkinson disease:[18F] fluorodopa positron emission tomographic study
JO Rinne, R Portin, H Ruottinen, E Nurmi… - Archives of …, 2000 - jamanetwork.com
Objective To investigate the role of the brain dopaminergic system in cognitive impairment in
patients with Parkinson disease (PD). Design We studied 28 patients with PD and 16 age …
patients with Parkinson disease (PD). Design We studied 28 patients with PD and 16 age …
Age dependence of 18F-fluorodopa uptake rate and dopamine turnover PET markers and implications for Parkinson's disease progression
V Sossi, JE Holden, M Schulzer… - Journal of Cerebral …, 2005 - journals.sagepub.com
Methods Nine healthy volunteers (age 58.1±11.8 yrs, range 43–76) underwent a 4hrs long
FD scan. Four 61 mm 2 circular regions of interest (ROIs) were placed on each striatum, and …
FD scan. Four 61 mm 2 circular regions of interest (ROIs) were placed on each striatum, and …
Automated striatal uptake analysis of 18F-FDOPA PET images applied to Parkinson's disease patients
IC Chang, KH Lue, HJ Hsieh, SH Liu… - Annals of nuclear …, 2011 - Springer
Abstract Objective 6-[18 F] Fluoro-l-DOPA (FDOPA) is a radiopharmaceutical valuable for
assessing the presynaptic dopaminergic function when used with positron emission …
assessing the presynaptic dopaminergic function when used with positron emission …