A digital revolution in radiosynthesis
DE Reichert - Journal of Nuclear Medicine, 2014 - Soc Nuclear Med
The rapid growth in the use of PET has led to a concomitant demand in the availability of
imaging tracers and research directed toward more efficient and flexible radiosynthetic …
imaging tracers and research directed toward more efficient and flexible radiosynthetic …
Automated synthesis modules for PET radiochemistry
L Bruton, PJH Scott - Handbook of radiopharmaceuticals …, 2020 - Wiley Online Library
The field of radiochemistry is constantly evolving to meet the needs for increased starting
amounts of radioactivity, and in the last couple of decades it has seen a move from manual …
amounts of radioactivity, and in the last couple of decades it has seen a move from manual …
Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer
J Collins, CM Waldmann, C Drake… - Proceedings of the …, 2017 - National Acad Sciences
New radiolabeled probes for positron-emission tomography (PET) are providing an ever-
increasing ability to answer diverse research and clinical questions and to facilitate the …
increasing ability to answer diverse research and clinical questions and to facilitate the …
Fully automated production of diverse 18F-labeled PET tracers on the ELIXYS multireactor radiosynthesizer without hardware modification
Fully automated radiosynthesizers are continuing to be developed to meet the growing need
for the reliable production of PET tracers made under current good manufacturing practice …
for the reliable production of PET tracers made under current good manufacturing practice …
Facilitating the design and operation of computer-controlled radiochemistry synthesizers with an “electronic toolbox”
AL Feliu - New Trends in Radiopharmaceutical Synthesis, Quality …, 1991 - Springer
Abstract Positron emission tomography (PET) 1, 2 is a non-invasive diagnostic imaging
technique in which short-lived radioactive tracers are used to selectively measure the …
technique in which short-lived radioactive tracers are used to selectively measure the …
Diverse nucleophilic syntheses on the ELIXYS multi-pot, cassette-based radiosynthesizer
1484 Objectives In order to facilitate development of new PET probes, a means to safely and
routinely synthesize a wide variety of PET probes on a single platform is required. Methods …
routinely synthesize a wide variety of PET probes on a single platform is required. Methods …
Economical Production of Radiopharmaceuticals for Preclinical Imaging Using Microdroplet Radiochemistry
J Wang, RM van Dam - Biomedical Engineering Technologies: Volume 1, 2022 - Springer
The short-lived radiolabeled “tracers” needed for performing whole body imaging in animals
or patients with positron-emission tomography (PET) are generally produced via automated …
or patients with positron-emission tomography (PET) are generally produced via automated …
A versatile, commercially available automated synthesizer for the development and production of PET radiotracers
ED Hostetler, TG Hamill, BE Francis… - Journal of Labelled …, 2001 - Wiley Online Library
The automation of routinely produced radiotracers is an important process for any PET
center. Automation allows frequent, highly reproducible syntheses with large amounts of …
center. Automation allows frequent, highly reproducible syntheses with large amounts of …
Sequential preparation of two different PET radiotracers employing the Advion NanoTek synthesis system
289 Objectives A configuration of the NanoTek LF was developed that allows for the
preparation of two radiotracers sequentially using a single setup of the system and using two …
preparation of two radiotracers sequentially using a single setup of the system and using two …
[CITATION][C] Automated PET radiosyntheses using microfluidic devices
CJ Steel, AT O'brien, SK Luthra… - Journal of Labelled …, 2007 - Wiley Online Library
Microfluidic devices can be used to achieve rapid synthesis times whilst providing a highly
controlled reaction environment. These factors, in conjunction with their small size and …
controlled reaction environment. These factors, in conjunction with their small size and …