1257 Objectives: Yttrium-90-polymer-composite (radiogel) may be administered directly into
cancerous tissues to deliver highly localized beta radiation for therapy. In a dose-escalation …

Purpose: Yttrium-90 (90Y)-polymer composite (radiogel) may be administered directly into
cancerous tissues to deliver highly localized beta radiation for therapy. In a dose-escalation …

Abstract Yttrium-90 (90 Y)-polymer composite (RadioGel™) is a new cancer therapeutic
agent for treating solid tumors by direct interstitial injection. The 90 Y-composite comprises …

SUMMARY AND CONCLUSIONS y90, in the form of yttrium hydroxide, impregnated into Gel-
foam and placed extraor intradurally in normal cats produces necrosis. A sharp border zone …

GRID directs alternating regions of high-and low-dose radiation at tumors. A large animal
model mimicking the geometries of human treatments is needed to complement existing …

PURPOSE: The alpha-particle-emitting isotope Bi-212 and its immediate upstream parent
Pb-212 are short-lived radiometals capable of delivering an intense but highly focussed …

Background Internal radiotherapy requires the localization of the radionuclide to the site of
action. A new injectable alginate gel formulation intended to undergo immediate gelation in …

Local recurrence of feline soft tissue sarcomas is common despite aggressive treatment.
Liposomal doxorubicin might serve as a depot radiosensitizer if administered concomitantly …

A new treatment strategy based on direct injections of 90 Y-hydroxide into the tumor bed in
dogs with osteosarcoma was studied. Direct injections of the radiopharmaceutical into the …

Brain tumors such as glioblastoma reappear in their original location in almost 50% of
cases. To prevent this recurrence, we developed a radiopharmaceutical system that consists …