SV2A PET imaging is a noninvasive marker for the detection of spinal damage in experimental models of spinal cord injury
D Bertoglio, N Halloin, S De Lombaerde… - Journal of nuclear …, 2022 - Soc Nuclear Med
Traumatic spinal cord injury (SCI) is a neurologic condition characterized by long-term motor
and sensory neurologic deficits as a consequence of an external physical impact damaging …
and sensory neurologic deficits as a consequence of an external physical impact damaging …
Feasibility of imaging synaptic density in the human spinal cord using 11C-UCB-J PET
112 Introduction: In vivo measurements of synaptic density in the spinal cord (SC) can
provide benefits in the study of conditions such as SC injury 1 and amyotrophic lateral …
provide benefits in the study of conditions such as SC injury 1 and amyotrophic lateral …
[HTML][HTML] Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET
Purpose Neuronal damage and synapse loss in the spinal cord (SC) have been implicated
in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral …
in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral …
[HTML][HTML] Longitudinal [18F] FDG and [13N] NH3 PET/CT imaging of brain and spinal cord in a canine hemisection spinal cord injury model
L Zhang, FR López-Picón, Y Jia, Y Chen, J Li, C Han… - NeuroImage: Clinical, 2021 - Elsevier
To further understand the neurological changes induced by spinal cord injury (SCI) in its
acute and subacute stages, we evaluated longitudinal changes in glucose and glutamate …
acute and subacute stages, we evaluated longitudinal changes in glucose and glutamate …
Positron emission tomography for serial imaging of the contused adult rat spinal cord
RDSN Tewarie, J Yu, J Seidel, ST Rahiem… - Molecular …, 2010 - journals.sagepub.com
We investigated whether small-animal positron emission tomography (PET) could be used
in combination with computed tomography (CT) imaging techniques for longitudinal …
in combination with computed tomography (CT) imaging techniques for longitudinal …
[HTML][HTML] In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [18F]GE-180 and effect of docosahexaenoic acid
JL Tremoleda, O Thau-Zuchman, M Davies… - European Journal of …, 2016 - Springer
Purpose Traumatic spinal cord injury (SCI) is a devastating condition which affects millions
of people worldwide causing major disability and substantial socioeconomic burden. There …
of people worldwide causing major disability and substantial socioeconomic burden. There …
Advanced MRI biomarkers of the injured spinal cord–a comparative study of imaging and histology in human traumatic SCI
SR Morris, T Swift-LaPointe, A Yung… - Journal of …, 2024 - liebertpub.com
A significant problem in the diagnosis and treatment of traumatic spinal cord injury (tSCI) is
the heterogeneity of secondary injury and the prediction of neurologic outcome. Imaging …
the heterogeneity of secondary injury and the prediction of neurologic outcome. Imaging …
[11C] UCB-J: a novel PET tracer for imaging the synaptic vesicle glycoprotein 2A (SV2A)
N Nabulsi, J Hannestad, D Holden, J Mercier… - 2014 - Soc Nuclear Med
355 Objectives Studies involving transgenic mice suggest that the antiepileptic drug
levetiracetam (LEV, Keppra®) binds to SVA2 that is known to be involved in vesicle …
levetiracetam (LEV, Keppra®) binds to SVA2 that is known to be involved in vesicle …
First-in-human evaluation of 18F-SDM-8, a novel radiotracer for PET imaging of synaptic vesicle Glycoprotein 2A
49 Objectives: Synaptic abnormalities are associated with many brain disorders, including
Alzheimer's disease, epilepsy, depression and schizophrenia. We have previously reported …
Alzheimer's disease, epilepsy, depression and schizophrenia. We have previously reported …
[HTML][HTML] Correlation of in vivo and ex vivo 1H-MRI with histology in two severities of mouse spinal cord injury
HN Noristani, N Lonjon, M Cardoso… - Frontiers in …, 2015 - frontiersin.org
Spinal cord injury (SCI) is a debilitating neuropathology with no effective treatment. Magnetic
resonance imaging (MRI) technology is the only method used to assess the impact of an …
resonance imaging (MRI) technology is the only method used to assess the impact of an …
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