Hematotoxicity after Radioligand Therapy with 177Lu-PSMA-617 in Patients with Metastastic Prostate Cancer

D Gröner, J Baumgarten, K Davis, C Happel, CN Ngoc… - 2020 - Soc Nuclear Med
594 Introduction: Myelosuppression may be a dose-limiting factor in repeated cycles of
radioligand therapy (RLT). This study aims to investigate the incidence, severity and …

[HTML][HTML] Hematologic safety of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer

D Groener, CT Nguyen, J Baumgarten, B Bockisch… - EJNMMI research, 2021 - Springer
Background Myelosuppression is a potential dose-limiting factor in radioligand therapy
(RLT). This study aims to investigate occurrence, severity and reversibility of hematotoxic …

Hematotoxicity after radioligand therapy of metastatic castrate-resistant prostate cancer with 177Lu-PSMA-617

S Zimbelmann, E Eppard, S Hauser, S Kuerpig… - 2016 - Soc Nuclear Med
1429 Objectives Radioligand therapy (RLT) with 177Lu-PSMA-617 (Lu-PSMA)(prostate-
specific membrane antigen) is a novel targeted therapy for metastatic prostate cancer. There …

Radioligand therapy with 177Lu-PSMA-617 in patients with diffuse bone marrow involvement: safety and efficacy results

D Gröner, CN Ngoc, K Davis, C Happel, J Baumgarten… - 2020 - Soc Nuclear Med
1280 Introduction: Advanced stage metastatic prostate cancer with extensive bone marrow
involvement is related to a high risk of chemotherapy-induced myelotoxicity and poor …

[HTML][HTML] Radioligand therapy of metastatic prostate cancer using 177Lu-PSMA-617 after radiation exposure to 223Ra-dichloride

H Ahmadzadehfar, S Zimbelmann, A Yordanova… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Radioligand therapy with 177 Lu-PSMA-617 is an innovative and effective therapy for
castrate-resistant metastatic prostate cancer patients. For patients with symptomatic bone …

[HTML][HTML] Salvage Radioligand Therapy with Repeated Cycles of 177Lu-PSMA-617 in Metastatic Castration-Resistant Prostate Cancer with Diffuse Bone Marrow …

D Groener, J Baumgarten, S Haefele, C Happel… - Cancers, 2021 - mdpi.com
Simple Summary Metastatic castration-resistant prostate cancer (mCRPC) with extensive
spread to the bone marrow is an incurable stage of disease associated with a poor …

[HTML][HTML] Hematotoxicity and Nephrotoxicity in Prostate Cancer Patients Undergoing Radioligand Therapy with [177Lu]Lu-PSMA I&T

PE Hartrampf, FX Weinzierl, SE Serfling, MG Pomper… - Cancers, 2022 - mdpi.com
Simple Summary Radioligand therapy (RLT) with prostate-specific membrane antigen
(PSMA)-directed agents has shown remarkable results in patients with advanced prostate …

German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients

K Rahbar, H Ahmadzadehfar… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177Lu-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy
(RLT) of patients with metastatic castration-resistant prostate cancer (mCRPC). Initiated by …

Nephro-and hepatotoxicity after radioligand therapy of metastatic castrate-resistant prostate cancer with 177Lu-PSMA-617

A Becker, E Eppard, S Kuerpig, C Fisang, A Yordanova… - 2016 - Soc Nuclear Med
1430 Objectives Radioligand therapy (RLT) with 177Lu-PSMA-617 (Lu-PSMA)(prostate-
specific membrane antigen) is a novel targeted therapy for metastatic prostate cancer. There …

Response and tolerability of a single dose of 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer: a multicenter retrospective analysis

K Rahbar, M Schmidt, A Heinzel, E Eppard… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Radiolabeled prostate-specific membrane antigen (PSMA) ligands represent a true
theranostic concept for diagnosis and therapy in patients with relapsed or metastatic …