Characterising the performance of the simplified and pseudo reference tissue models
2070 Objectives The simplified reference tissue model (SRTM) is a kinetic analysis method
that is commonly used to quantify brain PET studies and does not require the measurement …
that is commonly used to quantify brain PET studies and does not require the measurement …
Simplifying our understanding of SRTM
258 Objectives The simplified reference tissue model (SRTM) is a valuable tool for the
quantitative estimation of binding potential (BP ND) from dynamic PET. SRTM obviates the …
quantitative estimation of binding potential (BP ND) from dynamic PET. SRTM obviates the …
The impact of parameter bound selection in the simplified reference tissue method on the accuracy and quality of parametric images
359 Objectives: In PET tracer kinetic modeling (KM), the simplified reference tissue method
(SRTM) proposed by (Gunn et al., 1997) and SRTM2 developed by (Wu and Carson, 2002) …
(SRTM) proposed by (Gunn et al., 1997) and SRTM2 developed by (Wu and Carson, 2002) …
Beware of artificial tissue fraction effect in PET simulated images
P Huet, S Burg, I Buvat - 2015 - Soc Nuclear Med
1817 Objectives Many groups use Monte Carlo (MC) simulations involving voxelized activity
map to assess PET quantification methods in realistic conditions. Yet, how the spatial …
map to assess PET quantification methods in realistic conditions. Yet, how the spatial …
Quantification of PET tracer specific binding without reference tissue
361 Objectives: It is still challenging to quantify PET tracer specific binding reliably without
reference tissue. The objective of the study is to evaluate a physiological constraint kinetic …
reference tissue. The objective of the study is to evaluate a physiological constraint kinetic …
FDG-PET kinetic model identifiability and selection using machine learning
2431 Introduction: 18 F-FDG-PET is sensitive to malignant tumors because it reflects
increased uptake of glucose by tumour cells. The two-tissue compartment kinetic model …
increased uptake of glucose by tumour cells. The two-tissue compartment kinetic model …
The simplified reference tissue model: model assumption violations and their impact on binding potential
CA Salinas, GE Searle… - Journal of Cerebral Blood …, 2015 - journals.sagepub.com
Reference tissue models have gained significant traction over the last two decades as the
methods of choice for the quantification of brain positron emission tomography data because …
methods of choice for the quantification of brain positron emission tomography data because …
Controlling the false positive rate for lp-ntPET: A correction to goodness of fit metrics for''effective''number of parameters
H Liu, E Morris - 2019 - Soc Nuclear Med
580 Objectives: Linear parametric neurotransmitter PET 1 (lp-ntPET) is a novel kinetic model
that uses discrete basis functions to estimate the temporal characteristics of neurotransmitter …
that uses discrete basis functions to estimate the temporal characteristics of neurotransmitter …
Compartmental model with plasma input versus reference tissue model for quantification of ligand-receptor dynamic PET studies
335 Objectives: To evaluate three reference tissue models (RTMs) as compared to the
compartmental model with plasma input for quantification of ligand-receptor dynamic PET …
compartmental model with plasma input for quantification of ligand-receptor dynamic PET …
A regularized full reference tissue model for PET neuroreceptor mapping
The full reference tissue model (FRTM) is a PET analysis framework that includes both free
and specifically bound compartments within tissues, together with rate constants defining …
and specifically bound compartments within tissues, together with rate constants defining …