Tc-99m DMSARenalUptake:Influenceof BiochemicalandPhysiologicFactors Page 1 Available
data are inadequate concerning the physi ologic mechanisms of localization of the major …

METHODS Two different series of experiments were performed. One con sisted of
micropuncture collection experiments from surface glomeruliandfromproximalanddistaltubules …

Critical factors determining the renal handling of 99m Tc-dimercaptosuccinic acid (DMSA)
are protein binding in plasma and the renal 99m Tc-DMSA extraction efficiency. Comparison …

DMSA is an excellent static imaging agent. Approximately 50% of the injected dose remains
bound to the cortical tubules of the kidney up to 24 hr after injection. During this time, 30% of …

MATERIALS AND METHODS Our model involved 14 mongrel dogs, divided into two
categories: five control animals and nine with unilateral renal disease. The latter were sub …

The finding of an enhanced excretion of [99mTc] dimercaptosuccinic acid (DMSA) in patients
with tubular reabsorption disorders prompted us to investigate the role of filtration in the …

DMSA in Rats with Proximal Page 1 1974, technetium-99m 2,3 dimercaptosuccinic acid ([99mTc]DMSA)
was introduced as a substitute for radioactive mercury containing compounds for stat ic …

kidneys Page 1 Nuclear Medicine Communications 8,869–880 (1987) Relative and absolute
"Tc"-DMSA uptake measurements in normal and obstructed kidneys ZANANIRI MC., JARRITT …

In order to investigate aspects of the renal handling of 99m Tc-DMSA, 68 isolated rat kidneys
were artificially perfused. The experimental groups were: Group 1 (no.= 32)–oxygenated …

A renal uptake of 99mTc-DMSA as a function of time and correlation between 99mTc-DMSA
and 99mTc-DTPA in renal uptake were discussed. The absolute renal uptake of 99mTc …