Assessment of 11C-PE2I binding to the neuronal dopamine transporter in humans with the high-spatial-resolution PET scanner HRRT

C Leroy, C Comtat, R Trébossen, A Syrota… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The high-resolution research tomograph (HRRT), dedicated to brain imaging, may offer new
perspectives for identifying small brain nuclei that remain neglected by the spatial resolution …

Age-related decline in dopamine transporter in human brain using PET with a new radioligand [18F]FE-PE2I

Y Shingai, A Tateno, R Arakawa, T Sakayori… - Annals of nuclear …, 2014 - Springer
Objective Dopamine transporter (DAT) density is considered as a marker of pre-synaptic
function. Numerous neuroimaging studies have consistently demonstrated an age-related …

Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I

T Sasaki, H Ito, Y Kimura, R Arakawa… - Journal of Nuclear …, 2012 - Soc Nuclear Med
18F-(E)-N-(3-iodoprop-2 E-enyl)-2β-carbofluoroethoxy-3β-(4-methylphenyl) nortropane (18F-
FE-PE2I) is a new PET radioligand with a high affinity and selectivity for the dopamine …

Measurement of Striatal and Extrastriatal Dopamine Transporter Binding with High-Resolution PET and [11C]PE2I: Quantitative Modeling and Test—Retest …

J Hirvonen, J Johansson, M Teräs… - Journal of Cerebral …, 2008 - journals.sagepub.com
[11C] PE2I is a novel positron emission tomography (PET) radiotracer for the dopamine
transporter (DAT). The reproducibility and reliability of [11C] PE2I measurements, especially …

Optimal acquisition time window and simplified quantification of dopamine transporter availability using 18F-FE-PE2I in healthy controls and Parkinson disease …

I Sonni, P Fazio, M Schain, C Halldin… - Journal of Nuclear …, 2016 - Soc Nuclear Med
18F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4′ methylphenyl) nortropane (18F-
FE-PE2I) is a newly developed dopamine transporter (DAT) PET radioligand. Full …

Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study

A Jucaite, I Odano, H Olsson, S Pauli, C Halldin… - European journal of …, 2006 - Springer
Purpose The dopamine transporter (DAT) is a plasma membrane protein of central interest
in the pathophysiology of neuropsychiatric disorders and is known to be a target for …

Effect of age and gender on dopamine transporter imaging with [123I]FP-CIT SPET in healthy volunteers

J Lavalaye, J Booij, L Reneman, JBA Habraken… - European journal of …, 2000 - Springer
Dopamine transporter imaging is a valuable tool to investigate the integrity of the
dopaminergic neurons. To date, several reports have shown an age-associated decline in …

Quantitative analysis of dopamine transporters in human brain using [11C]PE2I and positron emission tomography: evaluation of reference tissue models

C Seki, H Ito, T Ichimiya, R Arakawa, Y Ikoma… - Annals of nuclear …, 2010 - Springer
Objective Dopamine transporter (DAT) is a reuptake carrier of dopamine at presynapse that
regulates dopaminergic neural transmission.[11 C] PE2I is a cocaine analog developed as a …

Reproducibility of [123I]PE2I binding to dopamine transporters with SPECT

M Ziebell, G Thomsen, GM Knudsen, R de Nijs… - European journal of …, 2007 - Springer
Purpose The iodinated cocaine derivative [123 I] PE2I is a new selective ligand for in vivo
studies of the dopamine transporter (DAT) with SPECT. Recently, a bolus/infusion (B/I) …

Validation of a method for accurate and highly reproducible quantification of brain dopamine transporter SPECT studies

PS Jensen, M Ziebell, G Skouboe… - Journal of Nuclear …, 2011 - Soc Nuclear Med
In nuclear medicine brain imaging, it is important to delineate regions of interest (ROIs) so
that the outcome is both accurate and reproducible. The purpose of this study was to …