Mesothelin is a cell-surface glycoprotein restricted to mesothelial cells overexpressed in
several types of cancer, including triple-negative breast cancer not responding to …

INTRODUCTION: Mesothelin is expressed in many cancers, especially in mesothelioma and
lung, pancreatic and ovarian cancers. In the present study, we evaluate 111In labeled …

Mesothelin is a membrane-associated protein overexpressed in pancreatic ductal
adenocarcinoma (PDAC). Some mesothelin-targeted therapies are in clinical development …

Purpose The aim of this review is to summarize the main applications of mesothelin-
targeting agents in the diagnosis of different types of cancers with a brief mention of nuclear …

Amatuximab is a chimeric high-affinity monoclonal IgG1/k antibody targeting mesothelin that
is being developed for treatment of mesothelin-expressing cancers. Considering the …

The mesothelin (MSLN)-targeted 227Th conjugate is a novel α-therapy developed to treat
MSLN-overexpressing cancers. We radiolabeled the same antibody–chelator conjugate with …

Mesothelin is a glycoprotein that is overexpressed in several human tumors, including
mesotheliomas and ovarian cancers, and has been identified as a potential target for …

Mesothelin is a cell surface associated antigen expressed on mesothelial cells and in some
malignant neoplasms. Mesothelin-targeted therapies are in phase I/II clinical trials. The …

Simple Summary This review summarizes the current knowledge on mesothelin's function,
its role in cancer, and opportunities for immunotherapeutic targeting of mesothelin …

Mesothelin is a cell-surface glycoprotein present on mesothelial cells and elicits T cell
responses in a variety of cancers including pancreatic, biliary and ovarian cancer. Breast …