Whole-body PET/CT was used to characterize the radiation dosimetry of 11C-DPA-713, a
specific PET ligand for the assessment of translocator protein. Methods: Six healthy control …

1007 Objectives:. Whole body PET/CT imaging was performed using 124 I-iodo-DPA-713, a
radioligand for translocator protein (TSPO), specific for activated macrophages, to determine …

Purpose To determine the metabolic profiles of the translocator protein ligands PBR102 and
PBR111 in rat and human microsomes and compare their in vivo binding and metabolite …

Abstract Purpose [18 F] FEDAA1106 is a recently developed positron emission tomography
(PET) radioligand for in vivo quantification of the 18 kDa translocator protein [TSPO or, as …

Translocator protein (TSPO) is expressed at a low level in healthy brain and is upregulated
during inflammatory processes that may occur in neurodegenerative diseases. Thus, TSPO …

Translocator protein (TSPO) is upregulated in activated microglia and thus can serve as a
marker of neuroinflammation. Recently, a novel radioligand, 11C-N, N-diethyl-2-[2-(4 …

Whole-body PET/CT was performed using 124I-DPA-713, a radioligand for the 18-kDa
translocator protein (TSPO), to determine biodistribution and radiation dosimetry. Methods …

This study details the synthesis, radio fluorination and evaluation of DPA-714, a new high
affinity pyrazopyrimidine for the TSPO.{sup 18} F DPA-714 is a highly specific radioligand for …

The translocator protein (TSPO; 18 kDa), formerly known as the peripheral benzodiazepine
receptor (PBR), is minimally expressed in the healthy brain. On the other hand, increased …

Abstract Introduction 11 C-DPA-713 is a positron emission tomography (PET) radiotracer
developed for imaging the expression of the translocator protein (TSPO) in glial cells, which …