Recent data have generated some interest in technetium-99m-(99mTc) glucaric acid as an
in vivo viability marker. We studied 99mTc-glucaric acid retention in canine models of …

Background. Current clinical approaches may not always be helpful in the early
differentiation of necrotic tissue from ischemic viable myocardium in patients with acute …

99mTc-stannous glucoheptonate (TcSnG) was evaluated in 5 mongrel dogs three to six
hours after intravenous administration of the radiopharmaceutical following surgical ligation …

201 (300— 500MCi) was administeredintravenouslyand anterior myocardial images were
recorded 10 mm later with the camera peaked at the 80 keV x-ray with a 20% window. At the …

99mTc-Glucarate is an infarct-avid imaging agent with the potential for very early detection
of myocardial infarction. The purposes of this study using a canine model were to determine …

Background Similar to other 99m Tc-based infarct-avid agents, 99m Tc-glucarate localizes in
myocardial infarcts. Whether severely ischemic viable myocytes sequester 99m Tc-glucarate …

Background 99mTc glucarate has recently been reported to be an infarct-avid agent. The
feasibility of imaging with 99mTc glucarate was evaluated for the early diagnosis of …

Recent advances in understanding of the pathophyslology of myocardial necrosis indicate
the need for a noninvaslve method that will allow detection and quantification of infarcts in …

The distribution of 99mTc-glucoheptonate in normal mice and its accumulation in acutely
infarcted myocardium were studied in animals. Rapid blood clearance and low …

Background Technetium-99m glucarate is a myocardial infarct-avid imaging agent. Recent
conflicting and inconclusive reports have suggested that the agent may be taken up by …