Targeted radiotherapy: is the “holy grail” in sight?

C Mothersill, CB Seymour - Journal of Nuclear Medicine, 2006 - Soc Nuclear Med
The ''Holy Grail''of radiotherapy is to find a treatment or technique that can maximize tumor
cell sterilization, minimize normal tissue damage, and be refractive to selection for …

The current status of targeted radiotherapy in clinical practice

MN Gaze - Physics in Medicine & Biology, 1996 - iopscience.iop.org
Biologically targeted radiotherapy in clinical practice requires a molecule which has a
relative specificity for tumour tissue-the missile-coupled to a radionuclide with appropriate …

[CITATION][C] Author correction: Radiotherapy toxicity

D De Ruysscher, G Niedermann… - Nature Reviews …, 2019 - cris.maastrichtuniversity.nl
Author Correction: Radiotherapy toxicity — Maastricht University Skip to main navigation Skip
to search Skip to main content Maastricht University Home Maastricht University Logo Support …

Dosimetric principles of targeted radiotherapy

J O'Donoghue - … of cancer. New York: Marcel Dekker, 2000 - api.taylorfrancis.com
For disseminated or diffuse malignant disease a systemic approach to treatment is required.
To achieve selective and systemic therapy simultaneously has been a longstanding …

The future of radioligand therapy: α, β, or both?

U Haberkorn, F Giesel, A Morgenstern… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Endoradiotherapy approaches are experiencing growing interest with the increase in the
number of carrier molecules becoming available for different targets. The cross-fire effect …

Targeted radiotherapy: microgray doses and the bystander effect

RJ Mairs, NE Fullerton, MR Zalutsky… - Dose-Response, 2007 - journals.sagepub.com
Indirect effects may contribute to the efficacy of radiotherapy by sterilizing malignant cells
that are not directly irradiated. However, little is known of the influence of indirect effects in …

Lisa Bodei, Jason S. Lewis, Brian M. Zeglis (Editors): Radiopharmaceutical Therapy

L Mansi - 2024 - Springer
It is enough to read the forewords of the book, written by Steven M. Larson, Emeritus at the
Memorial Sloan Kettering Cancer Center (MSKCC), one of the scientists who have …

Predicted allowable doses to normal organs for biologically targeted radiotherapy

JA O'Donoghue, TE Wheldon - The British Journal of Radiology, 1988 - academic.oup.com
Interest is growing in the use of radiolabelled molecules to deliver ionizing radiation to
tumour cells. Both monoclonal antibodies (Carrasquillo et al, 1984; Hammersmith Oncology …

Recent developments in radiotherapy

DE Citrin - New England journal of medicine, 2017 - Mass Medical Soc
Recent Developments in Radiotherapy | NEJM Skip to main content NEJM Group Follow Us
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …

Radiation quality‐dependent bystander effects elicited by targeted radionuclides

M Boyd, A Sorensen, AG McCluskey… - Journal of Pharmacy …, 2008 - Wiley Online Library
The efficacy of radiotherapy may be partly dependent on indirect effects, which can sterilise
malignant cells that are not directly irradiated. However, little is known of the influence of …