PET imaging of tumor-associated macrophages with 89Zr-labeled high-density lipoprotein nanoparticles
C Pérez-Medina, J Tang, D Abdel-Atti… - Journal of nuclear …, 2015 - Soc Nuclear Med
Tumor-associated macrophages (TAMs) are increasingly investigated in cancer immunology
and are considered a promising target for better and tailored treatment of malignant growth …
and are considered a promising target for better and tailored treatment of malignant growth …
A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting
C Pérez-Medina, D Abdel-Atti, Y Zhang… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Advances in preclinical molecular imaging have generated new opportunities to
noninvasively visualize the biodistribution and tumor targeting of nanoparticle therapeutics …
noninvasively visualize the biodistribution and tumor targeting of nanoparticle therapeutics …
Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals
A Helbok, C Decristoforo, G Dobrozemsky… - Journal of liposome …, 2010 - Taylor & Francis
Radiolabeling of nanoparticles (NPs) has been performed for a variety of reasons, such as
for studying pharmacokinetics, for imaging, or for therapy. Here, we describe the in vitro and …
for studying pharmacokinetics, for imaging, or for therapy. Here, we describe the in vitro and …
In vivo PET imaging of HDL in multiple atherosclerosis models
Objectives: The goal of this study was to develop and validate a noninvasive imaging tool to
visualize the in vivo behavior of high-density lipoprotein (HDL) by using positron emission …
visualize the in vivo behavior of high-density lipoprotein (HDL) by using positron emission …
Therapeutic efficacy and microSPECT/CT imaging of 188Re-DXR-liposome in a C26 murine colon carcinoma solid tumor model
YJ Chang, CH Chang, CY Yu, TJ Chang… - Nuclear medicine and …, 2010 - Elsevier
Nanocarriers can selectively target cancer sites and carry payloads, thereby improving
diagnostic and therapeutic effectiveness and reducing toxicity. The objective of this study …
diagnostic and therapeutic effectiveness and reducing toxicity. The objective of this study …
[HTML][HTML] The yin and yang of imaging tumor associated macrophages with PET and MRI
S Mukherjee, D Sonanini, A Maurer… - Theranostics, 2019 - ncbi.nlm.nih.gov
Tumor associated macrophages (TAM) are key players in the cancer microenvironment.
Molecular imaging modalities such as MRI and PET can be used to track and monitor TAM …
Molecular imaging modalities such as MRI and PET can be used to track and monitor TAM …
Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles
C Rangger, A Helbok, J Sosabowski… - International journal …, 2013 - Taylor & Francis
Background The significant progress in nanotechnology provides a wide spectrum of
nanosized material for various applications, including tumor targeting and molecular …
nanosized material for various applications, including tumor targeting and molecular …
Novel Method to Label Solid Lipid Nanoparticles with 64Cu for Positron Emission Tomography Imaging
Solid lipid nanoparticles (SLNs) are submicrometer (1− 1000 nm) colloidal carriers
developed in the past decade as an alternative system to traditional carriers (emulsions …
developed in the past decade as an alternative system to traditional carriers (emulsions …
[HTML][HTML] Companion diagnostic 64Cu-liposome positron emission tomography enables characterization of drug delivery to tumors and predicts response to cancer …
H Lee, D Gaddy, M Ventura, N Bernards… - Theranostics, 2018 - ncbi.nlm.nih.gov
Deposition of liposomal drugs into solid tumors is a potentially rate-limiting step for drug
delivery and has substantial variability that may influence probability of response. Tumor …
delivery and has substantial variability that may influence probability of response. Tumor …
A generic 89Zr labeling method to quantify the in vivo pharmacokinetics of liposomal nanoparticles with positron emission tomography
Liposomal nanoparticles are versatile drug delivery vehicles that show great promise in
cancer therapy. In an effort to quantitatively measure their in vivo pharmacokinetics, we …
cancer therapy. In an effort to quantitatively measure their in vivo pharmacokinetics, we …