Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer
The aim of this first-in-man study was to demonstrate the feasibility, safety, and tolerability,
as well as provide dosimetric data and evaluate the imaging properties, of the bombesin …
as well as provide dosimetric data and evaluate the imaging properties, of the bombesin …
18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors
M Honer, L Mu, T Stellfeld, K Graham… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Bombesin is a peptide exhibiting high affinity for the gastrin-releasing peptide receptor
(GRPr), which is highly overexpressed on prostate cancer cells. In the present study, we …
(GRPr), which is highly overexpressed on prostate cancer cells. In the present study, we …
[HTML][HTML] A standardised study to compare prostate cancer targeting efficacy of five radiolabelled bombesin analogues
RPJ Schroeder, C Müller, S Reneman, ML Melis… - European journal of …, 2010 - Springer
Purpose Prostate-specific antigen (PSA)-based screening for prostate cancer (PC) has
dramatically increased early diagnosis. Current imaging techniques are not optimal to stage …
dramatically increased early diagnosis. Current imaging techniques are not optimal to stage …
Nuclear imaging of prostate cancer with gastrin-releasing-peptide-receptor targeted radiopharmaceuticals
HJK Ananias, IJ De Jong, RA Dierckx… - Current …, 2008 - ingentaconnect.com
Prostate cancer is one of the most common causes of cancer in men. Evaluating the different
stages of prostate cancer with conventional imaging techniques still proves difficult. Nuclear …
stages of prostate cancer with conventional imaging techniques still proves difficult. Nuclear …
Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma
Bombesin (BBN), an analog of human gastrin-releasing peptide (GRP), binds to the GRP
receptor (GRPR) with high affinity and specificity. Overexpression of GRPR has been …
receptor (GRPR) with high affinity and specificity. Overexpression of GRPR has been …
Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin …
S Richter, M Wuest, SS Krieger, BE Rogers… - Nuclear Medicine and …, 2013 - Elsevier
Abstract Introduction Bombesin (BBN) and BBN analogues have attracted much attention as
high-affinity ligands for selective targeting of the gastrin-releasing peptide (GRP) receptor …
high-affinity ligands for selective targeting of the gastrin-releasing peptide (GRP) receptor …
In vitro and in vivo evaluation of 64Cu-labeled SarAr-bombesin analogs in gastrin-releasing peptide receptor–expressing prostate cancer
KA Lears, R Ferdani, K Liang… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Bombesin is a 14–amino-acid amphibian peptide that binds with high affinity to the gastrin-
releasing peptide receptor (GRPR), which is overexpressed on a variety of solid tumors. It …
releasing peptide receptor (GRPR), which is overexpressed on a variety of solid tumors. It …
An update of radiolabeled bombesin analogs for gastrin-releasing peptide receptor targeting
Z Yu, HJK Ananias, G Carlucci… - Current …, 2013 - ingentaconnect.com
Prostate cancer is a critical public health problem in USA and Europe. New non-invasive
imaging methods are urgently needed, due to the low accuracy and specificity of current …
imaging methods are urgently needed, due to the low accuracy and specificity of current …
Radiolabeled bombesin analogs for prostate cancer diagnosis: preclinical studies
BL Faintuch, R Teodoro, A Duatti, E Muramoto… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: Radionuclide imaging can be a useful tool for the diagnosis of prostate
cancer. Bombesin (BBN) is a molecule with high affinity for gastrin releasing peptide (GRP) …
cancer. Bombesin (BBN) is a molecule with high affinity for gastrin releasing peptide (GRP) …
In Vivo Imaging of Prostate Cancer Using [68Ga]-Labeled Bombesin Analog BAY86-7548
E Kähkönen, I Jambor, J Kemppainen, K Lehtiö… - Clinical cancer …, 2013 - AACR
Abstract Purpose: A novel [68Ga]-labeled DOTA-4-amino-1-carboxymethyl-piperidine-D-
Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 peptide (BAY86-7548) having high affinity to …
Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 peptide (BAY86-7548) having high affinity to …
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