D-Lysine Reduction of Indium- 111 Octreotide and Yttrium-90 Octreotide Renal Uptake Page 1
15. LoevingerR, BudingerTF, Watson EE. MIRO primer for absorbed dose calculations …

RESULTS In Table 1, the distribution of radioactivity in organs of control rats is shown,
expressed as percentage injected dose (% ID)/g tissue, 20 hr after administration of"" in …

As scintigraphy with [111 In-DTPA 0] octreotide has become a standard technique in
analysing somatostatin receptor-receptor positive lesions such as neuroendocrine tumours …

(Renografin) in Man' Page 1 JOURNAL OF NUCLEAR MEDICINE 6: 183-191, 1965 The
Renal Clearance of 131JLabeled Meglumine Diatrizoate (Renografin) in Man' Arthur M …

The high renal uptake of radiolabeled somatostatin analogs is dose limiting. Lowering this
uptake permits higher radioactivity doses and, thus, tumor doses to be administered. We …

RESULTS Expedment A Significant specific tissue binding of †œIn-pentetreotide was
observed in the octreotide receptor-positive anterior pituitary gland, adrenals, and pancreas …

The biodistribution of 111In-pentetreotide was assessed in patients with
gastroenteropancreatic (GEP) neuroendocrine tumors or lymphoma and in control patients …

In peptide receptor radionuclide therapy (PRRT) using somatostatin analogs labeled with β-
emitters, the radiosensitive kidney is the dose-limiting organ, because of high uptake and …

Methods: lndium-111 activityconcentrationsin human tumor and normal tissue samples were
determined at 24, 48 and 120 hr after iv injection of111ln-DTPA-D-Phe-1-octreotide …

Total-body retention. Data necessary for calcu lating the dose to the total body were
obtained by collecting excreta from patients injected with a sin gle iv dose of the compound …