We measured the uptake of the somatostatin receptor ligand 68Ga-[1, 4, 7, 10-
tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid]-d-Phe1, Tyr3-octreotate …

Activated macrophages which express somatostatin receptor-2 (SSTR-2) play a vital role in
rupture of the vulnerable atherosclerotic plaques, which result in death. 68 Ga-DOTATATE …

Abstract Background Ga-[1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic
acid]-d-Phe 1, Tyr 3-octreotate (DOTATATE) positron emission tomography (PET) is …

Background: Inflammation drives atherosclerotic plaque rupture. Although inflammation can
be measured using fluorine-18-labeled fluorodeoxyglucose positron emission tomography …

Formation and progression of atherosclerotic plaque is a dynamic and complex process
involving various pathophysiologic steps including inflammation and calcification. The …

The somatostatin receptor subtype 2 is expressed on macrophages, an abundant cell type in
the atherosclerotic plaque. Visualization of somatostatin receptor subtype 2, for oncologic …

PET/CT imaging with 18F-FDG has been used to detect inflammation in carotid and aortic
plaque; its use in detecting coronary plaque has been limited by avid 18F-FDG uptake by …

Background Coronary atherosclerosis and its thrombotic complications are the major cause
of mortality and morbidity throughout the industrialized world. Thrombosis on disrupted …

Purpose Measurements of [18 F] fluorodeoxyglucose (FDG) uptake as a potential marker of
the inflammatory activity of the vessel wall could be useful to identify vulnerable …

Objective—A feature of vulnerable atherosclerotic plaques of the carotid artery is high
activity and abundance of lesion macrophages. There is consensus that this is of importance …