Aim. To test for α2 adrenergic modulation of dopamine D2/3 receptor availability in striatum
of living mice using the high‐affinity ligand [18F] fallypride and microPET. Methods. Groups …

Abstract [18F] fallypride is a new positron emission tomography (PET) dopamine D2
receptor radiotracer that provides visualization of D2 receptors in both striatal and …

Aim. Molecular imaging studies with benzamide radioligands can reveal competition from
endogenous binding at D2/3‐receptors in living brain. However, single photon emission …

Rationale [18 F] Fallypride is a new and promising radiotracer, suitable for imaging D 2
receptors with Positron Emission Tomography (PET) in both striatal and extrastriatal regions …

We have used the high-affinity dopamine D-2 receptor radioligand, 18 F-fallypride for
evaluating receptor occupancy by the antipsychotic drugs, clozapine, risperidone, and …

Identification of dopamine D3 receptors (D3R) in vivo is important to understand several
brain functions related to addiction. The goal of this work was to identify D3R binding of the …

In this study, we compared two different D2/3 receptor ligands,[18F] fallypride and [18F]
desmethoxyfallypride ([18F] DMFP) with respect to the duration of the scan, visualization of …

Abstract [18F] Fallypride is a highly selective, high‐affinity dopamine D‐2 receptor ligand.
The high affinity, KD= 30 pM, makes it a suitable candidate for visualizing both striatal and …

The ability to measure amphetamine-induced dopamine release in extrastriatal brain
regions in the non-human primates was evaluated by using the dopamine D-2/D-3 receptor …

Molecular imaging has been used to estimate both drug‐induced and tonic dopamine
release in the striatum and most recently extrastriatal areas of healthy humans. However, to …