Imaging cancer metabolism: underlying biology and emerging strategies
AR Pantel, D Ackerman, SC Lee… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Dysregulated cellular metabolism is a characteristic feature of malignancy that has been
exploited for both imaging and targeted therapy. With regard to imaging, deranged glucose …
exploited for both imaging and targeted therapy. With regard to imaging, deranged glucose …
Imaging of tumor metabolism using positron emission tomography (PET)
I Apostolova, F Wedel, W Brenner - Metabolism in Cancer, 2016 - Springer
Molecular imaging employing PET/CT enables in vivo visualization, characterization, and
measurement of biologic processes in tumors at a molecular and cellular level. Using …
measurement of biologic processes in tumors at a molecular and cellular level. Using …
Imaging tumor metabolism using positron emission tomography
Positron emission tomography (PET) is an extraordinarily sensitive clinical imaging modality
for interrogating tumor metabolism. Radiolabeled PET substrates can be traced at …
for interrogating tumor metabolism. Radiolabeled PET substrates can be traced at …
[HTML][HTML] The sweet spot: FDG and other 2-carbon glucose analogs for multi-modal metabolic imaging of tumor metabolism
BL Cox, TR Mackie, KW Eliceiri - American journal of nuclear …, 2015 - ncbi.nlm.nih.gov
Multi-modal imaging approaches of tumor metabolism that provide improved specificity,
physiological relevance and spatial resolution would improve diagnosing of tumors and …
physiological relevance and spatial resolution would improve diagnosing of tumors and …
Tumor cell metabolism imaging
C Plathow, WA Weber - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging of tumor metabolism has gained considerable interest, since preclinical
studies have indicated a close relationship between the activation of various oncogenes and …
studies have indicated a close relationship between the activation of various oncogenes and …
[HTML][HTML] Positron emission tomography imaging of tumor cell metabolism and application to therapy response monitoring
A Challapalli, EO Aboagye - Frontiers in oncology, 2016 - frontiersin.org
Cancer cells do reprogram their energy metabolism to enable several functions, such as
generation of biomass including membrane biosynthesis, and overcoming bioenergetic and …
generation of biomass including membrane biosynthesis, and overcoming bioenergetic and …
[HTML][HTML] How we read oncologic FDG PET/CT
Abstract 18 F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer
imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy …
imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy …
Role of glutamine in cancer: therapeutic and imaging implications
KN Rajagopalan, RJ DeBerardinis - Journal of nuclear medicine, 2011 - Soc Nuclear Med
Metabolic imaging has great clinical potential in cancer because perturbations of
metabolism are common hallmarks of malignant cellular transformation. Novel imaging …
metabolism are common hallmarks of malignant cellular transformation. Novel imaging …
A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography
The high rate of glucose uptake to fuel the bioenergetic and anabolic demands of
proliferating cancer cells is well recognized and is exploited with 18F-2-fluoro-2-deoxy-d …
proliferating cancer cells is well recognized and is exploited with 18F-2-fluoro-2-deoxy-d …
Metabolic PET imaging in oncology
KKS Sai, Z Zachar, PM Bingham… - American Journal of …, 2017 - Am Roentgen Ray Soc
OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert
critical metabolic pathways to support their growth and unchecked division. Furthermore, we …
critical metabolic pathways to support their growth and unchecked division. Furthermore, we …