Dynamic FDG PET imaging using direct 4D parametric reconstruction in cancer patients

A Rahmim, M Lodge, J Tang, Y Zhou, B Hussain… - 2010 - Soc Nuclear Med
354 Objectives To investigate applicability of direct reconstruction of parametric images from
dynamic oncologic FDG PET data for the purpose of improved tumor detection. Methods A …

Towards parametric whole-body FDG PET/CT imaging: potentials for enhanced tumor detectability

N Karakatsanis, M Lodge, Y Zhou, J Mhlanga… - 2012 - Soc Nuclear Med
1236 Objectives Clinical whole-body PET/CT imaging currently involves static acquisitions
and employs SUV, a semi-quantitative metric with documented limitations. Our objective is to …

Direct 4D whole-body PET/CT parametric image reconstruction: concept and comparison vs. indirect parametric imaging

N Karakatsanis, M Lodge, R Wahl, A Rahmim - 2013 - Soc Nuclear Med
2133 Objectives Recently, indirect whole-body parametric PET/CT imaging, using Patlak
method, has been introduced to enhance tumor quantification and detectability in regions …

Feasibility of parametric imaging in multi-bed dynamic human FDG PET

Y Zhou, A Rahmim, M Lodge, H Jacene, R Pili, D Wong… - 2010 - Soc Nuclear Med
127 Objectives The Gjedde-Patlak plot (GP plot) is commonly used in quantitative dynamic
FDG PET studies. The uptake rate constant K i (mL/min/100 mL) can be theoretically …

Evaluation of whole-body parametric PET/CT image generation from high resolution high sensitivity mCT scanner

Y Zhou, M Lodge, J Crandall, N Karakatsanis, M Casey… - 2015 - Soc Nuclear Med
372 Objectives To evaluate a noninvasive whole-body parametric image generation
technique with high resolution PET-CT. Methods Patlak plot and a linear regression with …

[PDF][PDF] Enhanced FDG-PET tumor imaging with correlation-coefficient filtered influx-constant images

KR Zasadny, RL Wahl - Journal of Nuclear Medicine, 1996 - Soc Nuclear Med
Although FDG is an excellent PET tumor imaging agent, residual tracer activity in normal
structures such as blood vessels and the liver can impair the detection of small or modestly …

Novel multi-parametric SUV/Patlak FDG-PET whole-body imaging framework for routine application to clinical oncology

N Karakatsanis, M Lodge, Y Zhou, M Casey, R Wahl… - 2015 - Soc Nuclear Med
625 Objectives Standardized uptake value (SUV), although established in clinical oncology,
depends on post-injection (pi) scan times and patient metabolic state [1]. In this study, we …

Comparison of 2D and 3D performance for FDG PET with different acquisition times in oncological patients

G Komar, M Teräs, M Seppänen… - Nuclear medicine …, 2009 - journals.lww.com
Objective Collecting positron emission tomography data in three-dimensional (3D) mode
may potentially allow reduction of the tracer dose and/or the acquisition time without …

Impact of time-of-flight (TOF) and point-spread-function (PSF) PET on whole-body oncologic studies

P Alongi, M Picchio, V Bettinardi, AM Samanes… - 2012 - Soc Nuclear Med
2344 Objectives To evaluate the image quality (IQ) of the different reconstruction algorithms
in the novel hybrid Discovery 690 PET/CT system (GE Medical Systems) for both TOF and …

Dynamic whole-body PET parametric imaging: I. Concept, acquisition protocol optimization and clinical application

NA Karakatsanis, MA Lodge, AK Tahari… - Physics in Medicine …, 2013 - iopscience.iop.org
Static whole-body PET/CT, employing the standardized uptake value (SUV), is considered
the standard clinical approach to diagnosis and treatment response monitoring for a wide …