Tumor endothelial marker 1 (TEM1/endosialin) is a tumor vascular marker highly
overexpressed in multiple human cancers with minimal expression in normal adult tissue. In …

Tumor endothelial marker 1 (TEM1, endosialin) is a tumor vascular marker with significant
diagnostic and therapeutic potential. However, in vivo small animal models to test affinity …

Purpose Endosialin/tumor endothelial marker-1 (TEM1) is an attractive theranostic target
expressed by the microenvironment of a wide range of tumors, as well as by sarcoma and …

Background Tumour endothelial marker 1 (TEM1/endosialin/CD248) is a tumour-restricted
cell-surface protein expressed by human sarcomas. We previously developed a high-affinity …

Tumor endothelial marker 1 (Tem1; endosialin) is the prototypical member of a family of
genes expressed in the stroma of tumors. To assess the functional role of Tem1, we …

Abstract Endosialin (Tumor Endothelial Marker-1 (TEM-1), CD248) is primarily expressed on
pericytes of tumor-associated microvasculature, tumor-associated stromal cells and directly …

Human tumor endothelial marker 1/endosialin (TEM1/endosialin) was recently identified as
a novel tumor endothelial cell surface marker potentially involved in angiogenesis, although …

Endosialin (Tem1) has been identified by two independent experimental approaches as an
antigen of tumor-associated endothelial cells, and it has been claimed to be the most …

Background TEM1/endosialin is an emerging microvascular marker of tumor angiogenesis.
We characterized the expression pattern of TEM1/endosialin in astrocytic and metastatic …

TEM1 (endosialin) expression is increased in the stroma and tumor vasculature of several
common human cancers. The exact physiological role of TEM1 is still unknown since Tem1 …