Resection of tumors using targeted dual-modality probes combining preoperative imaging
with intraoperative guidance is of high clinical relevance and might considerably affect the …

Resection of tumor tissue represents one of the standard curative treatment options for the
clinical management of prostate cancer [1]. However, intraoperative localization and precise …

Background Due to its high and consistent expression in prostate cancer (PCa), the prostate-
specific membrane antigen (PSMA) represents an ideal target for molecular imaging and …

Despite many advances in the past years, the treatment of metastatic prostate cancer still
remains challenging. In recent years, prostate-specific membrane antigen (PSMA) inhibitors …

Introduction In this study, a structurally modified phosphoramidate scaffold, with improved
prostate-specific membrane antigen (PSMA) avidity, stability and in vivo characteristics, as a …

Expressed on virtually all prostate cancers and their metastases, the transmembrane protein
prostate-specific membrane antigen (PSMA) provides a valuable target for the imaging of …

The prostate-specific membrane antigen (PSMA)–targeted radiotracers 68Ga/177Lu-PSMA-
I&T and 99mTc-PSMA-I&S (for i maging and s urgery) are currently successfully used for …

68Ga-PSMA-11 is currently the most popular prostate-specific membrane antigen (PSMA)
radioligand used in the clinic to detect prostate cancer and metastases. However, the high …

Despite recent improvements in imaging and therapy, prostate cancer (PCa) still causes
substantial morbidity and mortality. In surgical treatment, incomplete resection of PCa and …

In the past two decades, extensive efforts have been made to develop agents targeting
prostate-specific membrane antigen (PSMA) for prostate cancer imaging and therapy. To …