[PDF][PDF] Comparison of technetium-99m-LL-EC isomers in rats and humans

A Taylor, L Hansen, D Eshima… - Journal of Nuclear …, 1997 - Soc Nuclear Med
MATERIALS AND METhODS L, L-ethylenedicysteine, D, D-ethylenedicysteine and a mixture
of D, DL, L-and D, L-ethylenedicysteine were prepared according to literature procedures …

Synthesis and biological evaluation of the four isomers of technetium-99m labeled ethylenecysteamine cysteine (99mTc-ECC), the mono-acid derivative of 99mTc-L, L …

HP Vanbilloen, BJ Cleynhens… - Nuclear medicine and …, 2000 - Elsevier
A few years ago 99mTc-ethylenedicysteine (99mTc-L, L-EC) had been proposed as an
interesting substitute for technetium-99m labeled mercaptoacetyltriglycine (MAG3) as renal …

Influence of a 99mTcN core on the biological and physicochemical behavior of 99mTc complexes of L, L-EC and L, L-ECD

KO Mang'era, HP Vanbilloen, E Bellande… - Nuclear medicine and …, 1996 - Elsevier
99mTc-nitrido complexes of L, L-ethylene dicysteine (99mTcN-L, L-EC) and 99mTcN-L, L-
ethylene dicysteine diethylester (99mTcN-L, L-ECD) were prepared and their characteristics …

Technetium-99m complexes of EDTA analogs: Studies of the radiochemistry and biodistribution

RJ Baker, CI Diamanti, DA Goodwin… - International Journal of …, 1981 - Elsevier
The preparation of technetium-99m aminopolycarboxylate complexes was carried out under
anerobic conditions using stannous ions as the reducing agent. Electrophoresis and thin …

On the nature of technetium compounds: 1. A semiquantitative biological model system to assay 99mTc-Complexes/Radiopharmaceuticals

OPD Noronha, KS Venkateswarlu - European Journal of Nuclear Medicine, 1981 - Springer
Eleven different 99m Tc compounds having some relevance in clinical nuclear medicine
have been classified according to their localizing properties. The following classes of 99m …

Effect of the Tc-nitrido group on the behaviour of 99mTc-radiopharmaceuticals

J Baldas, J Bonnyman - The International journal of applied radiation and …, 1985 - Elsevier
The preparation of the 99m TcN-complexes of gluconate, EHDP, HIDA and PIPIDA by
substitution reactions of 99m TcNCl 4− is described. Studies of the distribution of these …

Technetium-99m chelators in nuclear medicine. A review

OK Hjelstuen - Analyst, 1995 - pubs.rsc.org
Nuclear medicine is a branch of medical imaging that uses radioactive tracers to examine
the function of body systems. The radionuclide used in about 90% of all examinations is …

[PDF][PDF] Technetium-99m-L, L-ethylenedicysteine: a renal imaging agent. I. Labeling and evaluation in animals

AM Verbruggen, DL Nosco… - Journal of Nuclear …, 1992 - Soc Nuclear Med
Laboratory ofRadiopharmaceutical Chemistry JFW, KU Leuven and Department ofNuclear
Medicine, UZ Gasthuisberg, Leuven, Belgium; and Maiinckrodt Medical, Inc., St. Louis …

Stability versus reactivity of” 3+ 1” mixed-ligand technetium-99m complexes in vitro and in vivo

R Syhre, S Seifert, H Spies, A Gupta… - European journal of …, 1998 - Springer
Abstract.” 3+ 1” technetium-99m mixed-ligand complexes as relevant to the development of
a third generation of 99m Tc radiopharmaceuticals were investigated in vivo and in vitro in …

Technetium-99m: an historical perspective

P Richards, WD Tucker, SC Srivastava - Int. J. Appl. Radiat. Isot.;(United …, 1982 - osti.gov
The importance of/sup 99/Tc in the development of diagnostic nuclear medicine, over the
past 30 yrs. is discussed. Tc-99 is the ideal radiotracer and since the introduction and …