Regional 11C-hydroxyephedrine retention in hibernating myocardium: chronic inhomogeneity of sympathetic innervation in the absence of infarction

AJ Luisi, G Suzuki, R Dekemp, MS Haka… - Journal of Nuclear …, 2005 - Soc Nuclear Med
We have previously shown that ex vivo counting of 131I-metaiodobenzylguanidine can
identify regional reductions in sympathetic norepinephrine uptake in pigs with hibernating …

11C-meta-hydroxyephedrine defects persist despite functional improvement in hibernating myocardium

JA Fallavollita, MD Banas, G Suzuki… - Journal of nuclear …, 2010 - Elsevier
Background Regional cardiac sympathetic nerve dysfunction develops in hibernating
myocardium and may play a role in its association with sudden cardiac death. Interventions …

Pre-and post-synaptic sympathetic function in human hibernating myocardium

AS John, M Mongillo, C Depre, MT Khan… - European journal of …, 2007 - Springer
Purpose Impaired pre-synaptic noradrenaline uptake-1 mechanism has been reported in a
swine model of hibernating myocardium (HM). To ascertain whether adrenergic …

Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography.

M Schwaiger, V Kalff, K Rosenspire, MS Haka… - Circulation, 1990 - Am Heart Assoc
The noninvasive functional characterization of the cardiac sympathetic nervous system by
imaging techniques may provide important pathophysiological information in various cardiac …

Spatial inhomogeneity of sympathetic nerve function in hibernating myocardium

AJ Luisi Jr, JA Fallavollita, G Suzuki, JM Canty Jr - Circulation, 2002 - Am Heart Assoc
Background—Although humans and swine with hibernating myocardium have an increased
risk of sudden death, the contribution of chronic alterations in sympathetic nerve function is …

[HTML][HTML] Carbon-11 hydroxyephedrine with positron emission tomography for serial assessment of cardiac adrenergic neuronal function after acute myocardial …

KC Allman, DM Wieland, O Muzik, TR Degrado… - Journal of the American …, 1993 - Elsevier
Objectives. The purpose of this study was to assess the extent and reversibility of neuronal
abnormalities in patients with an acute myocardial infarction. Background. Previous …

[PDF][PDF] Quantitation of presynaptic cardiac sympathetic function with carbon-11-meta-hydroxyephedrine

JH Caldwell, K Kroll, Z Li, K Seymour… - Journal of Nuclear …, 1998 - Soc Nuclear Med
The purpose of this study was to validate an axially distributed blood-tissue exchange model
for the quantitation of cardiac presynaptic sympathetic nervous system function that could be …

Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?

MP Law, K Schäfers, K Kopka, S Wagner… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Dysfunction of the sympathetic nervous system underlies many cardiac diseases and can be
assessed by molecular imaging using PET in humans. Small-animal PET should enable …

In vivo PET imaging of cardiac presynaptic sympathoneuronal mechanisms in the rat

DN Tipre, JJ Fox, DP Holt, G Green, J Yu… - Journal of Nuclear …, 2008 - Soc Nuclear Med
The sympathetic nervous system of the heart plays a key role in the pathophysiology of
various cardiac diseases. Small-animal models are valuable for obtaining further insight into …

[PDF][PDF] Myocardial blood flow, function, and metabolism in repetitive stunning

MF Di Carli, P Prcevski, TP Singh… - Journal of nuclear …, 2000 - Soc Nuclear Med
Myocardial hibernation refers to a state of persistent left ventricu lar dysfunction resulting
from a chronically reduced blood flow, which is improved or reversed with revascularization …