Quantitative functional normal data should be a prerequisite before applying SPECT in
murine models of cardiac disease. Therefore, we investigated the capability of in vivo …

Purpose The aim of this study was to investigate the intra-individual reproducibility of left
ventricular volume and ejection fraction measurements in living rat using pinhole gated …

Background High-resolution single photon emission computed tomography (SPECT) with a
pinhole collimator is a new method for evaluating the regional properties of …

The rat infarct model is widely used to study left ventricular (LV) remodeling, a main cause of
heart failure characterized by progressive LV dilatation. Using pinhole collimators and …

The increasing use of transgenic mice as models of human physiology and disease has
motivated the development of dedicated in vivoimaging systems for anatomic and functional …

Ultra-high-resolution SPECT images can be obtained with focused multipinhole collimators.
Here we investigate the influence of unwanted high tracer uptake outside the scan volume …

Purpose: To prospectively determine feasibility of evaluating murine left ventricular (LV)
function with electrocardiographically (ECG)-gated blood pool single photon emission …

Ex vivo measurements in animals are used frequently in the field of nuclear medicine for the
characterization of newly developed radioligands and for drug development. In vivo SPECT …

Small animal imaging of cardiovascular disease using single photon emission tomography
(SPECT) can be used to provide quantitative measurements of myocardial infarct. The …

Conclusion We have reviewed the development of assessments of ventricular function by
use of gated MPS and the ways in which these measurements have contributed to the …