18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment
A Agool, BW Schot, PL Jager… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Few diagnostic procedures are available to determine the degree of bone marrow cellularity
and the numbers of cycling cells in patients with bone marrow disorders. Noninvasive …
and the numbers of cycling cells in patients with bone marrow disorders. Noninvasive …
First demonstration of leukemia imaging with the proliferation marker 18F-fluorodeoxythymidine
Acute myeloid leukemia (AML) is a neoplasm of hematopoietic stem cells with partial or
complete loss of the ability to differentiate but with preserved proliferation capacity. The aim …
complete loss of the ability to differentiate but with preserved proliferation capacity. The aim …
Effect of radiotherapy and chemotherapy on bone marrow activity: a 18F–FLT–PET study
A Agool, RHJA Slart, KK Thorp… - Nuclear medicine …, 2011 - journals.lww.com
Background Radiotherapy (RT) and chemotherapy are important treatment modalities for a
variety of malignant tumor types. During therapy for malignant diseases, often the limitation …
variety of malignant tumor types. During therapy for malignant diseases, often the limitation …
Correlations between 18F-FDG uptake by bone marrow and hematological parameters: measurements by PET/CT
Y Murata, K Kubota, M Yukihiro, K Ito… - Nuclear medicine and …, 2006 - Elsevier
The aim of this study was to investigate the correlations between 18F-FDG uptake by bone
marrow and various hematological parameters. Forty-eight patients who underwent FDG …
marrow and various hematological parameters. Forty-eight patients who underwent FDG …
18F-FDG dynamic PET/CT in patients with multiple myeloma: patterns of tracer uptake and correlation with bone marrow plasma cell infiltration rate
C Sachpekidis, EK Mai, H Goldschmidt… - Clinical nuclear …, 2015 - journals.lww.com
Purpose The value of 18 F-FDG PET in the diagnostic approach of multiple myeloma (MM)
remains incompletely elicited. Little is known about the kinetics of 18 F-FDG in the bone …
remains incompletely elicited. Little is known about the kinetics of 18 F-FDG in the bone …
[HTML][HTML] Increased bone marrow uptake of 18F-FDG in leukemia patients: preliminary findings
MK Arimoto, Y Nakamoto, K Nakatani, T Ishimori… - Springerplus, 2015 - Springer
The aim of this retrospective study was to evaluate the characteristics of increased bone
marrow uptake of 18F-FDG in patients with leukemia who underwent whole-body 18F-FDG …
marrow uptake of 18F-FDG in patients with leukemia who underwent whole-body 18F-FDG …
Effect of Platinum-Based Chemoradiotherapy on Cellular Proliferation in Bone Marrow and Spleen, Estimated by 18F-FLT PET/CT in Patients with Locally Advanced …
Historically, it has been difficult to monitor the acute impact of anticancer therapies on
hematopoietic organs on a whole-body scale. Deeper understanding of the effect of …
hematopoietic organs on a whole-body scale. Deeper understanding of the effect of …
[18F] 3'-Deoxy-3'-Fluorothymidine-PET in NHL Patients: Whole-Body Biodistribution and Imaging of Lymphoma Manifestations—a Pilot Study
I Buchmann, B Neumaier… - Cancer biotherapy & …, 2004 - liebertpub.com
Objective: The nucleoside 3′-deoxy-3′-fluorothymidine (alovudine) is an antiviral agent
accumulating in proliferating cells. We prospectively evaluated the biodistribution of the PET …
accumulating in proliferating cells. We prospectively evaluated the biodistribution of the PET …
[HTML][HTML] Radionuclide imaging of bone marrow disorders
A Agool, AWJM Glaudemans, HH Boersma… - European journal of …, 2011 - Springer
Noninvasive imaging techniques have been used in the past for visualization the functional
activity of the bone marrow compartment. Imaging with radiolabelled compounds may allow …
activity of the bone marrow compartment. Imaging with radiolabelled compounds may allow …
PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls
AF Shields - Journal of Nuclear Medicine, 2003 - Soc Nuclear Med
Medicine (1). Although the use of PET has exploded within the last few years, this has
primarily resulted from the application of 18F-FDG in oncology research and clinical …
primarily resulted from the application of 18F-FDG in oncology research and clinical …