[PDF][PDF] Glucose metabolism in human malignant gliomas measured quantitatively with PET, l-[C-ll] glucose and FDG: Analysis of the FDG lumped constant

AM Spence, M Muzi, MM Graham… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Calculation of the glucose metabolic rate (MRGIc) in brain with PET and 2-[18F] fluoro-2-
deoxy-D-glucose(FDG) requires knowing the rate of uptake of FDG relative to glucose from …

Kinetic characterization of hexokinase isoenzymes from glioma cells: implications for FDG imaging of human brain tumors

M Muzi, SD Freeman, RC Burrows… - Nuclear medicine and …, 2001 - Elsevier
Quantitative imaging of glucose metabolism of human brain tumors with PET utilizes 2-[18F]-
fluorodeoxy-D-glucose (FDG) and a conversion factor called the lumped constant (LC) …

[CITATION][C] Quantitating tumor glucose metabolism with FDG and PET

RA Hawkins, Y Choi, SC Huang, C Messa… - Journal of Nuclear …, 1992 - Soc Nuclear Med
The rate constants K* 1and k* 2refer to forward and reverse capillary trans port of FDG, while
k* 3 and k* 4 refer to phosphorylation of FDG and de phosphorylation of FDG-6-P04, re …

FDG transport and phosphorylation in human gliomas measured with dynamic PET

K Herholz, J Rudolf, WD Heiss - Journal of neuro-oncology, 1992 - Springer
Twenty-six patients with gliomas of WHO-grades two to four were examined with dynamic
positron emission tomography (PET) and 18 F-2-fluoro-2-deoxy-D-glucose (FDG). FDG rate …

[CITATION][C] PET-FDG of untreated and treated cerebral gliomas

G Di Chiro, RA Brooks - Journal of Nuclear Medicine, 1988 - Soc Nuclear Med
gests intrinsic metabolic differences between untreated tumors and tumors recurringafter
therapy, in which high LCMRG1 values have been observed (2, 4, 42). ― All of these three …

Glucose utilization of cerebral gliomas measured by [18F] fluorodeoxyglucose and positron emission tomography

G Di Chiro, RL DeLaPaz, RA Brooks, L Sokoloff… - Neurology, 1982 - AAN Enterprises
Positron emission tomography was used to measure local cerebral glucose utilization by the
2-[18F] fluoro-2-deoxy-D-glucose technique in 23 patients with cerebral gliomas. All 10 high …

The rate-limiting step for tumor [18F] fluoro-2-deoxy-D-glucose (FDG) incorporation

TAD Smith - Nuclear medicine and biology, 2001 - Elsevier
The enhanced rate of glucose utilization by tumor cells has been exploited in the imaging of
tumors using the radiolabelled glucose analogue fluoro-2-deoxy-D-glucose (FDG)[1], which …

Diagnostic and prognostic value of positron emission tomography using [18F] fluorodeoxyglucose in brain tumors

G DiChiro, RA Brooks, D Bairamian… - Positron emission …, 1985 - inis.iaea.org
[en] The predominance of the nonoxidative over the more efficient oxidative metabolic
pathway results in a higher glucose utilization rate in high-grade than in low-grade tumor …

Uncoupling of hexose transport and phosphorylation in human gliomas demonstrated by PET

K Herholz, P Ziffling, W Staffen, G Pawlik… - European Journal of …, 1988 - Elsevier
Abstract Tumor uptake of [18 F] 2-fluoro-2-deoxy-glucose (FDG) was studied in 20 patients
with histologically classified gliomas, using dynamic positron emission tomography (PET) …

[PDF][PDF] Effects of hyperglycemia on FDG uptake in human brain and glioma

K Ishizu, S Nishizawa, Y Yonekura… - Journal of Nuclear …, 1994 - Soc Nuclear Med
MATERIALSAND METhODS Subjects A totalof ten patients, seven malesandthreefemales,
mean age46. 3yr (range29to70yr), werestudied. Theyincludedeight gliomas, one metastatic …