MATERIALSAND METHODS Patients We studied 15 patients (8 men, 7 women; mean age,
38.4 ±12 y) with ileal CD diagnosed by conventional clinical, endo scopic, radiologic, and …

Crohn's disease (CD) is a chronic inflammatory bowel disease that may involve the whole
gut. Marked intestinal T cell and macrophage activation is a key feature of the disease …

The present study was undertaken to determine the value of indium-111 granulocyte
scintigraphy in Crohn's disease of the small bowel by comparing the results with those of …

Coeliac disease is diagnosed by the presence of specific antibodies and a jejunal biopsy
showing mucosal atrophy and mononuclear cell infiltration. Mucosal cell-mediated immune …

The diagnosis of inflammatory bowel disease (IBD) needs a complex diagnostic work-up.
Beside verifying the disease itself, it is fundamental to assess disease extent and activity and …

Quantification of disease activity in inflammatory bowel disease (IBD) has been by
measurement of fecal excretion of 111In-granulocytes. The difficulties of this method …

Radiolabeled autologous leukocytes (WBCs) are the gold standard for imaging inflammatory
bowel disease (IBD). For the rapid and adequate management of patients with IBD, there is …

Technetium-99m hexamethylpropylene amine oxime (HMPAO) labelled leucocytes and
indium-111 polyclonal immunoglobulin (IgG) were simultaneously injected into a group of …

A non-invasive method of imaging and assessing inflammatory bowel disease is described.
111Indium labelled leucocyte scans were performed on 33 patients with a wide variety of …

DISCUSSION This prospective study shows that early imagingwith@ †Tc-WBCsof patients
with IBD is superior to imaging with †œIn-granulocytes. This study confirms a previously …